Walid Radwan1, Brandon Lucke-Wold2, Ibrahim Ahmed Robadi3, Kymberly Gyure3, Thomas Roberts4, Sanjay Bhatia1. 1. Department of Neurosurgery, West Virginia University, Morgantown, West Virginia, USA. 2. West Virginia University, Morgantown, West Virginia, USA. 3. Department of Pathology, West Virginia University, Morgantown, West Virginia, USA. 4. Department of Radiology, West Virginia University, Morgantown, West Virginia, USA.
Abstract
BACKGROUND: Sarcoidosis is a chronic, multisystem disease characterised by non-necrotising granulomatous inflammation of unknown aetiology. Most commonly, the lungs, lymph nodes, skin and eyes are affected in sarcoidosis; however, nervous system involvement occurs in approximately 5%-15% of cases. Any part of the nervous system can be affected by sarcoidosis. CASES: Herein we describe three unusual patient presentations of neurosarcoidosis, one with optic neuritis, a second with hydrocephalus and a third with cervical myelopathy. CONCLUSIONS: We include pertinent details about their presentations, imaging findings, pathology, management and clinical course. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.
BACKGROUND:Sarcoidosis is a chronic, multisystem disease characterised by non-necrotising granulomatous inflammation of unknown aetiology. Most commonly, the lungs, lymph nodes, skin and eyes are affected in sarcoidosis; however, nervous system involvement occurs in approximately 5%-15% of cases. Any part of the nervous system can be affected by sarcoidosis. CASES: Herein we describe three unusual patient presentations of neurosarcoidosis, one with optic neuritis, a second with hydrocephalus and a third with cervical myelopathy. CONCLUSIONS: We include pertinent details about their presentations, imaging findings, pathology, management and clinical course. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.