Literature DB >> 27919396

Think time: A novel approach to analysis of clinicians' behavior after reduction of drug-drug interaction alerts.

Richard Schreiber1, Julia A Gregoire2, Jacob E Shaha3, Steven H Shaha4.   

Abstract

OBJECTIVES: Pharmacologic interaction alerting offers the potential for safer medication prescribing, but research reveals persistent concerns regarding alert fatigue. Research studies have tried various strategies to resolve this problem, with low overall success. We examined the effects of targeted alert reduction on clinician behavior in a resource constrained hospital.
METHODS: A physician and a pharmacy informaticist reduced alert levels of several drug-drug interactions (DDI) that clinicians almost always overrode with approval from and knowledge of the medical staff. This study evaluated the behavioral changes in prescribers and non-prescribers as measured by "think time", a new metric for evaluating the resolution time for an alert, before and after suppression of selected DDI alerts.
RESULTS: The user-seen DDI alert rate decreased from 9.98% of all orders to 9.20% (p=0.0001) with an overall volume reduction of 10.3%. There was no statistical difference in the reduction of cancelled (-10.00%) vs. proceed orders (-11.07%). Think time decreased overall by 0.61s (p<0.0001). Think time unexpectedly increased for cancelled orders 1.00s which while not statistically significant (p=0.28) is generally thought to be clinically noteworthy. For overrides, think time decreased 0.67s which was significant (p<0.0001). Think time lowered for both prescribers and non-prescribers. Targeted specialists had shorter think times initially, which shortened more than non-targeted specialists.
CONCLUSIONS: Targeted DDI alert reductions reduce alert burden overall, and increase net efficiency as measured by think time for all prescribers better than for non-prescribers. Think time may increase when cancelling or changing orders in response to DDI alerts vs. a decision to override an alert. Copyright Â
© 2016 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Alert fatigue; Clinical decision support; Drug-drug interactions; Pre-post evaluation; Think time

Mesh:

Year:  2016        PMID: 27919396     DOI: 10.1016/j.ijmedinf.2016.09.011

Source DB:  PubMed          Journal:  Int J Med Inform        ISSN: 1386-5056            Impact factor:   4.046


  7 in total

1.  Comparison of Overridden Medication-related Clinical Decision Support in the Intensive Care Unit between a Commercial System and a Legacy System.

Authors:  Adrian Wong; Adam Wright; Diane L Seger; Mary G Amato; Julie M Fiskio; David Bates
Journal:  Appl Clin Inform       Date:  2017-08-23       Impact factor: 2.342

2.  The Effect of Eliminating Intermediate Severity Drug-Drug Interaction Alerts on Overall Medication Alert Burden and Acceptance Rate.

Authors:  Amy M Knight; Joyce Maygers; Kimberly A Foltz; Isha S John; Hsin Chieh Yeh; Daniel J Brotman
Journal:  Appl Clin Inform       Date:  2019-12-04       Impact factor: 2.342

Review 3.  Advances in Clinical Decision Support: Highlights of Practice and the Literature 2015-2016.

Authors:  R A Jenders
Journal:  Yearb Med Inform       Date:  2017-09-11

Review 4.  Modulators Influencing Medication Alert Acceptance: An Explorative Review.

Authors:  Janina A Bittmann; Walter E Haefeli; Hanna M Seidling
Journal:  Appl Clin Inform       Date:  2022-08-18       Impact factor: 2.762

Review 5.  Clinical Decision Support Stewardship: Best Practices and Techniques to Monitor and Improve Interruptive Alerts.

Authors:  Juan D Chaparro; Jonathan M Beus; Adam C Dziorny; Philip A Hagedorn; Sean Hernandez; Swaminathan Kandaswamy; Eric S Kirkendall; Allison B McCoy; Naveen Muthu; Evan W Orenstein
Journal:  Appl Clin Inform       Date:  2022-05-25       Impact factor: 2.762

6.  Reducing Alert Burden in Electronic Health Records: State of the Art Recommendations from Four Health Systems.

Authors:  John D McGreevey; Colleen P Mallozzi; Randa M Perkins; Eric Shelov; Richard Schreiber
Journal:  Appl Clin Inform       Date:  2020-01-01       Impact factor: 2.342

7.  dfgcompare: a library to support process variant analysis through Markov models.

Authors:  Amin Jalali; Paul Johannesson; Erik Perjons; Ylva Askfors; Abdolazim Rezaei Kalladj; Tero Shemeikka; Anikó Vég
Journal:  BMC Med Inform Decis Mak       Date:  2021-12-20       Impact factor: 2.796

  7 in total

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