OBJECTIVE: This study evaluated the effect of TKA with capsulosynovectomy on disease activity and knee function in patients with RA. METHODS: Seventy-six RA patients who underwent primary TKA with more than two years of follow-up were retrospectively reviewed to assess postoperative knee function and disease activity. RESULTS: Postoperative knee function was significantly improved in all clinical scores, and maintained up to 24 months after surgery. RA disease activity was significantly decreased in DAS28-CRP, CDAI, and serum CRP level, and maintained up to 24 months after surgery. Postoperative knee function was negatively correlated with RA disease activity. CONCLUSIONS: TKA improves both knee function and disease activity in patients with rheumatoid arthritis.
OBJECTIVE: This study evaluated the effect of TKA with capsulosynovectomy on disease activity and knee function in patients with RA. METHODS: Seventy-six RApatients who underwent primary TKA with more than two years of follow-up were retrospectively reviewed to assess postoperative knee function and disease activity. RESULTS: Postoperative knee function was significantly improved in all clinical scores, and maintained up to 24 months after surgery. RA disease activity was significantly decreased in DAS28-CRP, CDAI, and serum CRP level, and maintained up to 24 months after surgery. Postoperative knee function was negatively correlated with RA disease activity. CONCLUSIONS: TKA improves both knee function and disease activity in patients with rheumatoid arthritis.
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Keywords:
Disease activity; Knee function; Rheumatoid arthritis; Total knee arthroplasty