Literature DB >> 27918115

An Amphiphilic Ruthenium Polymetallodrug for Combined Photodynamic Therapy and Photochemotherapy In Vivo.

Wen Sun1, Shuyi Li2, Bernhard Häupler3, Juan Liu2, Shubin Jin2, Werner Steffen1, Ulrich S Schubert3, Hans-Jürgen Butt1, Xing-Jie Liang2, Si Wu1.   

Abstract

An amphiphilic Ru-containing block copolymer is used as a photoactivated polymetallodrug for anticancer phototherapy. The block copolymer self-assembles into nanoparticles, which can accumulate at tumor sites in a mouse model. Red light irradiation of the block copolymer nanoparticles releases anticancer Ru complexes and generates cytotoxic 1 O2 , both of which can inhibit tumor growth.
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  metallodrugs; photochemotherapy; photodynamic therapy; polymers; ruthenium

Mesh：

Substances：

Year:  2016        PMID： 27918115     DOI： 10.1002/adma.201603702

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  19 in total

1.  Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials.

Authors:  Roy Weinstain; Tomáš Slanina; Dnyaneshwar Kand; Petr Klán
Journal:  Chem Rev       Date:  2020-10-30       Impact factor: 60.622

Review 2.  The development of anticancer ruthenium(ii) complexes: from single molecule compounds to nanomaterials.

Authors:  Leli Zeng; Pranav Gupta; Yanglu Chen; Enju Wang; Liangnian Ji; Hui Chao; Zhe-Sheng Chen
Journal:  Chem Soc Rev       Date:  2017-10-02       Impact factor: 54.564

3.  ROS-Responsive Polyprodrug Nanoparticles for Triggered Drug Delivery and Effective Cancer Therapy.

Authors:  Xiaoding Xu; Phei Er Saw; Wei Tao; Yujing Li; Xiaoyuan Ji; Sushant Bhasin; Yanlan Liu; Dana Ayyash; Jonathan Rasmussen; Marc Huo; Jinjun Shi; Omid C Farokhzad
Journal:  Adv Mater       Date:  2017-07-06       Impact factor: 30.849

4.  Red Light-Based Dual Photoredox Strategy Resembling the Z-Scheme of Natural Photosynthesis.

Authors:  Felix Glaser; Oliver S Wenger
Journal:  JACS Au       Date:  2022-06-10

5.  Photosubstitution in a trisheteroleptic ruthenium complex inhibits conjunctival melanoma growth in a zebrafish orthotopic xenograft model.

Authors:  Quanchi Chen; Jordi-Amat Cuello-Garibo; Ludovic Bretin; Liyan Zhang; Vadde Ramu; Yasmin Aydar; Yevhen Batsiun; Sharon Bronkhorst; Yurii Husiev; Nataliia Beztsinna; Lanpeng Chen; Xue-Quan Zhou; Claudia Schmidt; Ingo Ott; Martine J Jager; Albert M Brouwer; B Ewa Snaar-Jagalska; Sylvestre Bonnet
Journal:  Chem Sci       Date:  2022-05-16       Impact factor: 9.969

6.  Glutathione-Responsive Prodrug Nanoparticles for Effective Drug Delivery and Cancer Therapy.

Authors:  Xiang Ling; Jiasheng Tu; Junqing Wang; Aram Shajii; Na Kong; Chan Feng; Ye Zhang; Mikyung Yu; Tian Xie; Zameer Bharwani; Bader M Aljaeid; Bingyang Shi; Wei Tao; Omid C Farokhzad
Journal:  ACS Nano       Date:  2018-12-04       Impact factor: 15.881

Review 7.  Nanotechnology assisted photo- and sonodynamic therapy for overcoming drug resistance.

Authors:  Rui Li; Zhimin Chen; Zhifei Dai; Yingjie Yu
Journal:  Cancer Biol Med       Date:  2021-03-23       Impact factor: 4.248

8.  Light-activated gold nanorod vesicles with NIR-II fluorescence and photoacoustic imaging performances for cancer theranostics.

Authors:  Xiaoguang Ge; Qinrui Fu; Lichao Su; Zhi Li; Wenmin Zhang; Tao Chen; Huanghao Yang; Jibin Song
Journal:  Theranostics       Date:  2020-03-26       Impact factor: 11.556

Review 9.  Subcellular Performance of Nanoparticles in Cancer Therapy.

Authors:  Chen-Guang Liu; Ya-Hui Han; Ranjith Kumar Kankala; Shi-Bin Wang; Ai-Zheng Chen
Journal:  Int J Nanomedicine       Date:  2020-02-05

10.  Reconfiguring surface functions using visible-light-controlled metal-ligand coordination.

Authors:  Chaoming Xie; Wen Sun; Hao Lu; Annika Kretzschmann; Jiahui Liu; Manfred Wagner; Hans-Jürgen Butt; Xu Deng; Si Wu
Journal:  Nat Commun       Date:  2018-09-21       Impact factor: 14.919
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