Literature DB >> 2791710

Pharmacokinetics of miocamycin in patients with liver cirrhosis.

P A Miglioli1, P Pivetta, R Orlando, P Palatini, A Varotto, L Okolicsanyi.   

Abstract

The pharmacokinetics of miocamycin, a new macrolide antibiotic, was studied in 6 healthy controls and 6 patients with compensated liver cirrhosis. The results indicate that in chronic liver disease the kinetics of the drug is altered. Therefore, a dosage adjustment of miocamycin is recommended when dealing with these patients.

Entities:  

Mesh:

Substances:

Year:  1989        PMID: 2791710     DOI: 10.1159/000238690

Source DB:  PubMed          Journal:  Chemotherapy        ISSN: 0009-3157            Impact factor:   2.544


  2 in total

1.  Pharmacokinetics of dirithromycin in patients with mild or moderate cirrhosis.

Authors:  T Mazzei; C Surrenti; A Novelli; M R Biagini; S Fallani; M I Cassetta; S Conti; E Surrenti
Journal:  Antimicrob Agents Chemother       Date:  1999-07       Impact factor: 5.191

Review 2.  Miocamycin. A review of its antimicrobial activity, pharmacokinetic properties and therapeutic potential.

Authors:  S M Holliday; D Faulds
Journal:  Drugs       Date:  1993-10       Impact factor: 9.546

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.