Literature DB >> 27916648

NaV1.7 as a pain target - From gene to pharmacology.

Irina Vetter1, Jennifer R Deuis2, Alexander Mueller2, Mathilde R Israel2, Hana Starobova2, Alan Zhang3, Lachlan D Rash4, Mehdi Mobli3.   

Abstract

Entities:  

Keywords:  Congenital insensitivity to pain; Inherited erythromelalgia; Pain; Paroxysmal extreme pain disorder; Sensory neuron; Sodium channel

Mesh：

Substances：

Year:  2016        PMID： 27916648     DOI： 10.1016/j.pharmthera.2016.11.015

Source DB:  PubMed          Journal:  Pharmacol Ther        ISSN： 0163-7258            Impact factor:   12.310


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  38 in total

Review 1.  Flushing Disorders Associated with Gastrointestinal Symptoms: Part 2, Systemic Miscellaneous Conditions.

Authors:  Vaibhav Rastogi; Devina Singh; Joseph J Mazza; Dipendra Parajuli; Steven H Yale
Journal:  Clin Med Res       Date:  2018-04-12

2.  Manipulation of a spider peptide toxin alters its affinity for lipid bilayers and potency and selectivity for voltage-gated sodium channel subtype 1.7.

Authors:  Akello J Agwa; Poanna Tran; Alexander Mueller; Hue N T Tran; Jennifer R Deuis; Mathilde R Israel; Kirsten L McMahon; David J Craik; Irina Vetter; Christina I Schroeder
Journal:  J Biol Chem       Date:  2020-03-05       Impact factor: 5.157

3.  Voltage-gated Na+ currents in human dorsal root ganglion neurons.

Authors:  Xiulin Zhang; Birgit T Priest; Inna Belfer; Michael S Gold
Journal:  Elife       Date:  2017-05-16       Impact factor: 8.140

4.  Acyl Sulfonamides NaV1.7 Blockers Useful for the Treatment of Pain.

Authors:  Benjamin E Blass
Journal:  ACS Med Chem Lett       Date:  2018-02-05       Impact factor: 4.345

5.  Enhancing inactivation rather than reducing activation of Nav1.7 channels by a clinically effective analgesic CNV1014802.

Authors:  Yue-Ming Zheng; Wan-Fu Wang; Yan-Fen Li; Yong Yu; Zhao-Bing Gao
Journal:  Acta Pharmacol Sin       Date:  2017-11-02       Impact factor: 6.150

6.  Mapping the Molecular Surface of the Analgesic NaV1.7-Selective Peptide Pn3a Reveals Residues Essential for Membrane and Channel Interactions.

Authors:  Alexander Mueller; Zoltan Dekan; Quentin Kaas; Akello J Agwa; Hana Starobova; Paul F Alewood; Christina I Schroeder; Mehdi Mobli; Jennifer R Deuis; Irina Vetter
Journal:  ACS Pharmacol Transl Sci       Date:  2020-02-19

Review 7.  Mining the Nav1.7 interactome: Opportunities for chronic pain therapeutics.

Authors:  Lindsey A Chew; Shreya S Bellampalli; Erik T Dustrude; Rajesh Khanna
Journal:  Biochem Pharmacol       Date:  2019-01-27       Impact factor: 5.858

8.  A mutant of the Buthus martensii Karsch antitumor-analgesic peptide exhibits reduced inhibition to hNav1.4 and hNav1.5 channels while retaining analgesic activity.

Authors:  Yijia Xu; Xiangxue Meng; Xue Hou; Jianfang Sun; Xiaohua Kong; Yuqi Sun; Zeyu Liu; Yuanyuan Ma; Ye Niu; Yongbo Song; Yong Cui; Mingyi Zhao; Jinghai Zhang
Journal:  J Biol Chem       Date:  2017-09-18       Impact factor: 5.157

Review 9.  Basic/Translational Development of Forthcoming Opioid- and Nonopioid-Targeted Pain Therapeutics.

Authors:  Nebojsa Nick Knezevic; Ajay Yekkirala; Tony L Yaksh
Journal:  Anesth Analg       Date:  2017-11       Impact factor: 5.108

10.  From identification to functional characterization of cyriotoxin-1a, an antinociceptive toxin from the spider Cyriopagopus schioedtei.

Authors:  Tânia C Gonçalves; Evelyne Benoit; Michael Kurz; Laetitia Lucarain; Sophie Fouconnier; Stéphanie Combemale; Lucie Jaquillard; Brigitte Schombert; Jean-Marie Chambard; Rachid Boukaiba; Gerhard Hessler; Andrees Bohme; Laurent Bialy; Stéphane Hourcade; Rémy Béroud; Michel De Waard; Denis Servent; Michel Partiseti
Journal:  Br J Pharmacol       Date:  2019-04-09       Impact factor: 8.739
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