Literature DB >> 27916577

Association of fibrosis in the infrapatellar fat pad and degenerative cartilage change of patellofemoral joint after anterior cruciate ligament reconstruction.

Kyoung Ho Yoon1, Dae Hyun Tak1, Taeg Su Ko1, Sang Eon Park1, Juhyun Nam1, Sang Hak Lee2.   

Abstract

BACKGROUND: The purpose of this study was to evaluate the prevalence and risk factor of cartilage degeneration of the patellofemoral joint (PFJ) that was diagnosed by second-look arthroscopy.
METHODS: One-hundred and seven patients who underwent ACL reconstruction were evaluated by preoperative MRI, postoperative MRI and second-look arthroscopy. Severity of infrapatellar fat pad (IPFP) fibrosis was evaluated by MRI at an average of 26months after ACL reconstruction. Cartilage degeneration was assessed by second-look arthroscopy at 29months.
RESULTS: Twenty-five patients (24.0%) showed cartilage degeneration of the PFJ in second-look arthroscopy. Patients were divided into three groups according to severity of IPFP fibrosis of postoperative MRI (i.e. Group A, focal and incomplete band fibrosis, n=69; Group B, complete band fibrosis, n=31; and Group C, diffuse and infiltrated fibrosis, n=7). Cartilage degeneration of the PFJ was significantly worsened with more fibrosis formation of the IPFP (P<0.001). Other factors for instabilities (BMI, age, concomitant meniscal procedure, time from injury to reconstruction, severity of IPFP fibrosis at preoperative MRI and clinical scores) were not correlated with cartilage degeneration of the PFJ. The multivariate logistic regression analysis of degeneration of the PFJ after ACL reconstruction identified more severe fibrosis tissue formation of the IPFP and initial cartilage defect as significant predictors.
CONCLUSIONS: More extensive fibrosis of the IPFP and initial cartilage defect may be related to further degenerative changes of the PFJ. Other factors did not affect cartilage degeneration of the PFJ, although the muscle strength, the individual activity level or the rehabilitation protocol was not evaluated in the short-term follow-up period.
Copyright © 2016 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Anterior cruciate ligament; Cartilage degeneration; Infrapatellar fat pad; Magnetic resonance imaging; Patellofemoral joint

Mesh:

Year:  2017        PMID: 27916577     DOI: 10.1016/j.knee.2016.10.018

Source DB:  PubMed          Journal:  Knee        ISSN: 0968-0160            Impact factor:   2.199


  5 in total

1.  The infrapatellar fat pad is a dynamic and mobile structure, which deforms during knee motion, and has proximal extensions which wrap around the patella.

Authors:  Joanna M Stephen; Ran Sopher; Sebastian Tullie; Andrew A Amis; Simon Ball; Andy Williams
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2018-04-20       Impact factor: 4.342

2.  Inhibitory effect of low‑intensity pulsed ultrasound on the fibrosis of the infrapatellar fat pad through the regulation of HIF‑1α in a carrageenan‑induced knee osteoarthritis rat model.

Authors:  Takashi Kitagawa; Hirohisa Kawahata; Motokuni Aoki; Shintarou Kudo
Journal:  Biomed Rep       Date:  2022-08-09

3.  Relationship between the deep flexion of the knee joint and the dynamics of the infrapatellar fat pad after anterior cruciate ligament reconstruction via ultrasonography.

Authors:  Takashi Kitagawa; Junsuke Nakase; Yasushi Takata; Kengo Shimozaki; Kazuki Asai; Kazu Toyooka; Hiroyuki Tsuchiya
Journal:  J Phys Ther Sci       Date:  2019-07-09

4.  Flexibility of infrapatellar fat pad affecting anterior knee pain 6 months after anterior cruciate ligament reconstruction with hamstring autograft.

Authors:  Takashi Kitagawa; Junsuke Nakase; Yasushi Takata; Kengo Shimozaki; Kazuki Asai; Rikuto Yoshimizu; Mitsuhiro Kimura; Hiroyuki Tsuchiya
Journal:  Sci Rep       Date:  2020-12-07       Impact factor: 4.379

5.  Infrapatellar fat pad abnormalities are associated with a higher inflammatory synovial fluid cytokine profile in young adults following ACL tear.

Authors:  U Heilmeier; K Mamoto; K Amano; B Eck; M Tanaka; J A Bullen; B J Schwaiger; J L Huebner; T V Stabler; V B Kraus; C B Ma; T M Link; X Li
Journal:  Osteoarthritis Cartilage       Date:  2019-09-14       Impact factor: 6.576

  5 in total

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