Literature DB >> 27914964

Antioxidant and hemolytic activities, and effects in rat cutaneous wound healing of a novel polysaccharide from fenugreek (Trigonella foenum-graecum) seeds.

Naourez Ktari1, Imen Trabelsi2, Sana Bardaa3, Mehdi Triki2, Intidhar Bkhairia1, Rabab Ben Slama-Ben Salem1, Moncef Nasri1, Riadh Ben Salah4.   

Abstract

The aim of this work was to evaluate the antioxidant and hemolytic activities as well as the in vivo wound healing performance of a novel polysaccharide (FWEP) extracted from fenugreek (Trigonella foenum-graecum) seeds. The antioxidant activity was evaluated in vivo and in vitro using various assays. Results showed that FWEP exhibited strong antioxidant activities but no hemolytic activity was observed towards bovine erythrocytes. The application of FWEP hydrogel on the wound site in a rat model enhanced significantly wound healing activity and accelerated the wound closure after 14days of wound induction. Histological examination also demonstrated fully re-epithelialized wound with a complete epidermal regeneration. Altogether, these evidences demonstrated that FWEP had strong wound healing potential presumably achieved through its antioxidant activities.
Copyright © 2016 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Antioxidant activities; Fenugreek seeds; Hemolytic activity; Polysaccharide; Wound healing

Mesh：

Substances：

Year:  2016        PMID： 27914964     DOI： 10.1016/j.ijbiomac.2016.11.091

Source DB:  PubMed          Journal:  Int J Biol Macromol        ISSN： 0141-8130            Impact factor:   6.953


  7 in total

1.  A novel probiotic strain, Lactiplantibacillus plantarum LC38, isolated from Tunisian camel milk promoting wound healing in Wistar diabetic rats.

Authors:  Aicha Chouikhi; Naourez Ktari; Sana Bardaa; Amina Hzami; Sirine Ben Slima; Imen Trabelsi; Abdeslam Asehraou; Riadh Ben Salah
Journal:  Arch Microbiol       Date:  2021-12-17       Impact factor: 2.552

2.  Amebicidal effects of fenugreek (Trigonella foenum-graecum) against Acanthamoeba cysts.

Authors:  Yasemin Kaya; Ayşe Baldemir; Ülkü Karaman; Nilay Ildız; Yeliz Kasko Arıcı; Gamze Kaçmaz; Zeynep Kolören; Yusuf Konca
Journal:  Food Sci Nutr       Date:  2019-01-28       Impact factor: 2.863

3.  The inhibitory effects of isolated constituents from Plantago major subsp. major L. on collagenase, elastase and hyaluronidase enzymes: Potential wound healer.

Authors:  Yasin Genc; Fatma Tugce Guragac Dereli; Iclal Saracoglu; Esra Kupeli Akkol
Journal:  Saudi Pharm J       Date:  2019-12-07       Impact factor: 4.330

4.  Structure Analysis and Antioxidant Activity of a Novel Polysaccharide from Katan Seeds.

Authors:  Imen Trabelsi; Sirine Ben Slima; Naourez Ktari; Mohamed Bouaziz; Riadh Ben Salah
Journal:  Biomed Res Int       Date:  2021-01-12       Impact factor: 3.411

5.  Chemical Fingerprinting, Antioxidant, and Anti-Inflammatory Potential of Hydroethanolic Extract of Trigonella foenum-graecum.

Authors:  Hina Fatima; Muhammad Shahid; Chris Pruitt; Meredith A Pung; Paul J Mills; Muhammad Riaz; Rizwan Ashraf
Journal:  Antioxidants (Basel)       Date:  2022-02-11

6.  The Effects of Fenugreek Extract on Growth Performance, Serum Biochemical Indexes, Immunity and NF-κB Signaling Pathway in Broiler.

Authors:  Hui Huang; Xia Wang; Ling Yang; Wenxiang He; Tiantian Meng; Ke Zheng; Xin Xia; Yingjun Zhou; Jianhua He; Chunming Liu; Shengwen Zou; Dingfu Xiao
Journal:  Front Vet Sci       Date:  2022-06-23

7.  Extraction, Characterization, and Structure of a Novel Heteropolysaccharide from Lepidium sativum and Its Effects on Wound Healing in Diabetic Rats.

Authors:  Sirine Ben Slima; Naourez Ktari; Aicha Chouikhi; Amina Hzami; Sana Bardaa; Imen Trabelsi; Basma Ben Salah; Riadh Ben Salah
Journal:  Biomed Res Int       Date:  2022-08-23       Impact factor: 3.246
  7 in total

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