| Literature DB >> 27914924 |
Deepak Joshi1, Nitika Gupta2, Marianne Samyn3, Maesha Deheragoda3, Fabienne Dobbels4, Michael A Heneghan3.
Abstract
An increasing number of patients with childhood liver disease survive into adulthood. These young adults are now entering adult services and require ongoing management. Aetiologies can be divided into liver diseases that develop in young adults which present to adult hepatologists i.e., biliary atresia and Alagille syndrome or liver diseases that occur in children/adolescents and adults i.e., autoimmune hepatitis or Wilson's disease. To successfully manage these young adults, a dynamic and responsive transition service is essential. In this review, we aim to describe the successful components of a transition service highlighting the importance of self-management support and a multi-disciplinary approach. We will also review some of the liver specific aetiologies which are unique to young adults, offering an update on pathogenesis, management and outcomes.Entities:
Keywords: Adolescence; Autoimmune liver disease; Autoimmune sclerosing cholangitis; Biliary atresia; Cholestatic liver disease; Self-management; Transition
Mesh:
Year: 2016 PMID: 27914924 DOI: 10.1016/j.jhep.2016.11.013
Source DB: PubMed Journal: J Hepatol ISSN: 0168-8278 Impact factor: 25.083