Literature DB >> 27914759

Fluid Management in Patients with Trauma: Restrictive Versus Liberal Approach.

Lee Palmer1.   

Abstract

Massive hemorrhage remains a major cause of traumatic deaths. The ideal fluid resuscitative strategy is much debated. Research has provided inconsistent results regarding which fluid strategy is ideal; the optimum fluid type, timing, and volume remains elusive. Aggressive large-volume resuscitation has been the mainstay based on controlled hemorrhage animal models. For uncontrolled hemorrhagic shock, liberal fluid resuscitative strategies exacerbate the lethal triad, invoke resuscitative injury, and increase mortality while more restrictive fluid strategies tend to ameliorate trauma-induced coagulopathy and favor a greater chance of survival. This article discusses the current evidence regarding liberal and restrictive fluid strategies for trauma.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Damage controlled resuscitation; Hemorrhagic shock; Hemostatic resuscitation; Lethal triad; Permissive hypotension; Trauma

Mesh:

Year:  2016        PMID: 27914759     DOI: 10.1016/j.cvsm.2016.10.014

Source DB:  PubMed          Journal:  Vet Clin North Am Small Anim Pract        ISSN: 0195-5616            Impact factor:   2.093


  2 in total

1.  Comparison of the effects of 7.2% hypertonic saline and 20% mannitol on whole blood coagulation and platelet function in dogs with suspected intracranial hypertension - a pilot study.

Authors:  Ivayla D Yozova; Judith Howard; Diana Henke; Daniel Dirkmann; Katja N Adamik
Journal:  BMC Vet Res       Date:  2017-06-19       Impact factor: 2.741

2.  Effect of early restrictive fluid resuscitation on inflammatory and immune factors in patients with severe pelvic fracture.

Authors:  La-Mei Jiang; Jun He; Xiao-Yan Xi; Chun-Mei Huang
Journal:  Chin J Traumatol       Date:  2019-09-20
  2 in total

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