| Literature DB >> 27911493 |
David H Mathews1, Douglas H Turner1, Richard M Watson1.
Abstract
In this unit, protocols are provided for predicting RNA secondary structure with the user-friendly RNAstructure desktop computer program and the RNAstructure Web server. The minimum free energy structure and a set of suboptimal structures with similar free energies are predicted. Prediction of high-affinity oligonucleotide binding sites to a structured RNA target is also presented. © 2016 by John Wiley & Sons, Inc.Entities:
Keywords: RNA folding; RNA secondary structure prediction; binding affinity; free energy minimization; partition function; thermodynamics
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Year: 2016 PMID: 27911493 DOI: 10.1002/cpnc.19
Source DB: PubMed Journal: Curr Protoc Nucleic Acid Chem ISSN: 1934-9270