Literature DB >> 27911045

The Anticancer Potential of Ionic Liquids.

Ana Rita Dias1, João Costa-Rodrigues2,3,4, Maria Helena Fernandes2, Ricardo Ferraz1,5, Cristina Prudêncio1,6.   

Abstract

Among the many challenges that the pharmaceutical industry currently faces is the need to develop innovative and effective therapies. The investigation of alternative and effective therapies against cancer is a current goal of the pharmaceutical industry. Ionic liquids (ILs) have emerged recently as a topic of study by researchers in the pharmaceutical industry in their search for new therapeutic agents. By definition, ILs are organic salts with melting points below 100 °C that are composed only by ions. Their main advantage lies in the numerous possible combinations of cations and anions, which allow adjustments in their physicochemical properties. The combination between ILs and active pharmaceutical ingredients (APIs) may improve the properties of APIs. In addition, the antitumor properties of these compounds have been described. Several studies have reported the use of ILs in biomedical applications as therapeutic agents, namely as antitumor agents. This review describes the recent proposed applications of ILs as antitumor agents.
© 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  active pharmaceutical ingredients; antitumor agents; cancer; ionic liquids; toxicity

Mesh:

Substances:

Year:  2016        PMID: 27911045     DOI: 10.1002/cmdc.201600480

Source DB:  PubMed          Journal:  ChemMedChem        ISSN: 1860-7179            Impact factor:   3.466


  8 in total

Review 1.  Ionic Liquid-Based Polymer Nanocomposites for Sensors, Energy, Biomedicine, and Environmental Applications: Roadmap to the Future.

Authors:  Kirti Mishra; Nishu Devi; Samarjeet Singh Siwal; Qibo Zhang; Walaa F Alsanie; Fabrizio Scarpa; Vijay Kumar Thakur
Journal:  Adv Sci (Weinh)       Date:  2022-07-19       Impact factor: 17.521

Review 2.  New Potential Agents for Malignant Melanoma Treatment-Most Recent Studies 2020-2022.

Authors:  Paweł Kozyra; Danuta Krasowska; Monika Pitucha
Journal:  Int J Mol Sci       Date:  2022-05-29       Impact factor: 6.208

3.  1-Benzyl-3-cetyl-2-methylimidazolium Iodide (NH125) Is a Broad-Spectrum Inhibitor of Virus Entry with Lysosomotropic Features.

Authors:  Sarah Moeschler; Samira Locher; Gert Zimmer
Journal:  Viruses       Date:  2018-06-05       Impact factor: 5.048

4.  Upgrading the Topical Delivery of Poorly Soluble Drugs Using Ionic Liquids as a Versatile Tool.

Authors:  Rita Caparica; Ana Júlio; Filipe Fernandes; Maria Eduarda M Araújo; João Guilherme Costa; Tânia Santos de Almeida
Journal:  Int J Mol Sci       Date:  2021-04-21       Impact factor: 5.923

5.  Fine-tuning of the pharmacological potential of novel thiazolium ionic liquids by anion alteration.

Authors:  Mohammad Y Alfaifi; Ali A Shati; Serag Eldin I Elbehairi; Reda F M Elshaarawy; Emad M Gad
Journal:  RSC Adv       Date:  2021-12-22       Impact factor: 3.361

6.  Natural Variation in the Multidrug Efflux Pump SGE1 Underlies Ionic Liquid Tolerance in Yeast.

Authors:  Douglas A Higgins; Megan K M Young; Mary Tremaine; Maria Sardi; Jenna M Fletcher; Margaret Agnew; Lisa Liu; Quinn Dickinson; David Peris; Russell L Wrobel; Chris Todd Hittinger; Audrey P Gasch; Steven W Singer; Blake A Simmons; Robert Landick; Michael P Thelen; Trey K Sato
Journal:  Genetics       Date:  2018-07-25       Impact factor: 4.562

Review 7.  Ionic Liquids Toxicity-Benefits and Threats.

Authors:  Jolanta Flieger; Michał Flieger
Journal:  Int J Mol Sci       Date:  2020-08-29       Impact factor: 5.923

8.  "Clicking" an Ionic Liquid to a Potent Antimicrobial Peptide: On the Route towards Improved Stability.

Authors:  Ana Gomes; Lucinda J Bessa; Patrícia Correia; Iva Fernandes; Ricardo Ferraz; Paula Gameiro; Cátia Teixeira; Paula Gomes
Journal:  Int J Mol Sci       Date:  2020-08-26       Impact factor: 5.923

  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.