Literature DB >> 27909624

For reliable urine cultures in the detection of complicated urinary tract infection, do we use urine specimens obtained with urethral catheter or a nephrostomy tube?

Gülay Dede1, Özcan Deveci2, Onur Dede3, Mazhar Utanğac3, Mansur Dağgulli3, Necmettin Penbegül3, Namık Kemal Hatipoğlu3.   

Abstract

OBJECTIVE: The aim of this study was to compare the results of urine cultures obtained either from urethral, and percutaneous nephrostomy (PCN) catheters.
MATERIALS AND METHODS: This study included 328 consecutive patients that underwent PCN at our institution with complicated urinary tract infections (UTIs) between July 2010 and April 2015. Results of urine cultures obtained from the urethral and nephrostomy catheters were compared.
RESULTS: This study included 152 male and 176 female patients. Mean age of the patients was 46.2±24.3 years. The main indications were obstructive uropathy due to urolithiasis complicated with pyonephrosis 145 (44%), malignant disease (n=87; 26%), pregnancy (n=26; 8%), and anatomical abnormality (n=23; 7%). One hundred and twenty three patients had diabetes mellitus. The most common causative organisms were Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa. Blood cultures showed the same results for the PCN and bladder urine cultures. The bladder urine culture was positive in 304 patients, while the PCN urine culture in 314 patients.
CONCLUSION: PCN is an important treatment for the management of pyonephrosis. Cultures from the PCN yield valuable information that is not available from urethral urine cultures, and is a guiding tool for antibiotic therapy selection.

Entities:  

Keywords:  Complicated urinary tract infection; percutaneous nephrostomy culture; urethral culture

Year:  2016        PMID: 27909624      PMCID: PMC5125745          DOI: 10.5152/tud.2016.00947

Source DB:  PubMed          Journal:  Turk J Urol        ISSN: 2149-3235


  13 in total

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Authors:  Parvati Ramchandani; John F Cardella; Clement J Grassi; Anne C Roberts; David Sacks; Marc S Schwartzberg; Curtis A Lewis
Journal:  J Vasc Interv Radiol       Date:  2003-09       Impact factor: 3.464

2.  Experiments with induced bacteriuria, vesical emptying and bacterial growth on the mechanism of bladder defense to infection.

Authors:  C E COX; F HINMAN
Journal:  J Urol       Date:  1961-12       Impact factor: 7.450

Review 3.  Complicated urinary tract infections: practical solutions for the treatment of multiresistant Gram-negative bacteria.

Authors:  Ann Pallett; Kieran Hand
Journal:  J Antimicrob Chemother       Date:  2010-11       Impact factor: 5.790

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Authors:  V Spoorenberg; J M Prins; B C Opmeer; T M de Reijke; M E J L Hulscher; S E Geerlings
Journal:  Clin Microbiol Infect       Date:  2014-01-13       Impact factor: 8.067

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Authors:  B R McMurray; K D Wrenn; S W Wright
Journal:  Am J Emerg Med       Date:  1997-03       Impact factor: 2.469

Review 6.  Urinary tract infections.

Authors:  Carol E Chenoweth; Sanjay Saint
Journal:  Infect Dis Clin North Am       Date:  2010-12-18       Impact factor: 5.982

7.  Stone and pelvic urine culture and sensitivity are better than bladder urine as predictors of urosepsis following percutaneous nephrolithotomy: a prospective clinical study.

Authors:  Paramananthan Mariappan; Gordon Smith; Simon V Bariol; Sami A Moussa; David A Tolley
Journal:  J Urol       Date:  2005-05       Impact factor: 7.450

Review 8.  A practical guide to the management of complicated urinary tract infection.

Authors:  L E Nicolle
Journal:  Drugs       Date:  1997-04       Impact factor: 9.546

Review 9.  Complicated urinary tract infections.

Authors:  Durwood E Neal
Journal:  Urol Clin North Am       Date:  2008-02       Impact factor: 2.241

10.  Pyonephrosis: diagnosis and treatment.

Authors:  M St Lezin; R Hofmann; M L Stoller
Journal:  Br J Urol       Date:  1992-10
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