Literature DB >> 27909594

Knowledge of the Research Assistants Regarding Local Anaesthetics and Toxicity.

Derya Karasu1, Canan Yılmaz1, Şeyda Efsun Özgünay1, Mürüvvet Dayıoğlu1, Çağdaş Baytar1, Gülsen Korfalı1.   

Abstract

OBJECTIVE: Cardiovascular system depression, respiratory arrest, coma, convulsions, loss of consciousness, muscle twitching, blurred vision, vertigo, dizziness and numbness of the tongue can be seen in local anaesthetic toxicity. Treatment includes 20% lipid solutions, airway control, symptomatic treatment for arrhythmia and convulsions. The aim of this study is to present the knowledge of research assistants, who used local anaesthetics in daily practice, regarding these medications and toxicity treatment and to raise awareness.
METHODS: The questionnaire comprising 20 questions was administered to 115 research assistants who worked at different specialities in our hospital.
RESULTS: One hundred and two (88.6%) research assistants answered the questionnaire. Participants' mean age was 28.93 years. Most of them were from the Emergency Department (15.7%). A total of 40.6% of participants worked for 2-5 years at their departments. Local anaesthetics were used in daily practice for 44.4% of them, but 70.3% of them had not been educated about local anaesthetics. Research assistants from anaesthesiology and reanimation participated at a significantly higher rate than other departments (76.9%), in terms of training programs regarding local anaesthetics. While the most popular answers about early toxicity symptoms were anaphylaxis (12.7%) and arrthymia (12.7%), late toxicity was hepatotoxicity (10.8%). However, 87.9% of participants had never encountered local anaesthetic toxicity. The great majority of participants had never heard of lipid therapy (67.4%), and those who were aware had heard it from their trainers (52.2%). Although lipid solution was available in our hospital, only 8.4% of participants knew this.
CONCLUSION: We believe that additional training programs regarding local anaesthetics and toxicity are needed.

Entities:  

Keywords:  Local anaesthetic; questionnaire; toxicity

Year:  2016        PMID: 27909594      PMCID: PMC5019871          DOI: 10.5152/TJAR.2016.53138

Source DB:  PubMed          Journal:  Turk J Anaesthesiol Reanim        ISSN: 2149-276X


  8 in total

1.  American Society of Regional Anesthesia and Pain Medicine checklist for managing local anesthetic systemic toxicity: 2012 version.

Authors:  Joseph M Neal; Michael F Mulroy; Guy L Weinberg
Journal:  Reg Anesth Pain Med       Date:  2012 Jan-Feb       Impact factor: 6.288

2.  Limited knowledge of lipid rescue therapy in local anaesthetic systemic toxicity.

Authors:  Peter Jensen-Gadegaard; Martin Skjønnemand; Jens Damgaard-Jensen; Bo Gottschau
Journal:  Dan Med Bull       Date:  2011-01

Review 3.  Local anesthetic systemic toxicity.

Authors:  David M Dickerson; Jeffrey L Apfelbaum
Journal:  Aesthet Surg J       Date:  2014-07-15       Impact factor: 4.283

Review 4.  A Review of Local Anesthetic Systemic Toxicity Cases Since Publication of the American Society of Regional Anesthesia Recommendations: To Whom It May Concern.

Authors:  Francesco Vasques; Astrid U Behr; Guy Weinberg; Carlo Ori; Guido Di Gregorio
Journal:  Reg Anesth Pain Med       Date:  2015 Nov-Dec       Impact factor: 6.288

Review 5.  Past, Present, and Future of Lipid Resuscitation Therapy.

Authors:  Michael R Fettiplace; Guy Weinberg
Journal:  JPEN J Parenter Enteral Nutr       Date:  2015-07-17       Impact factor: 4.016

6.  Systemic toxicity to local anesthesia in an infant undergoing circumcision.

Authors:  Ayşe Belin Özer; Ömer Lütfi Erhan
Journal:  Agri       Date:  2014

7.  Late Local Anaesthetic Toxicity After Infraclavicular Block Procedure.

Authors:  Hansa İnceöz; Zehra Baykal Tutal; Münire Babayiğit; Akın Kepek; Eyüp Horasanlı
Journal:  Turk J Anaesthesiol Reanim       Date:  2015-02-16

8.  Lidocaine-Induced Cardiac Arrest in the Emergency Department: Effectiveness of Lipid Therapy.

Authors:  Kevin James Tierney; Tiffany Murano; Brenda Natal
Journal:  J Emerg Med       Date:  2015-10-23       Impact factor: 1.484

  8 in total
  4 in total

1.  Lidocaine Infusion: An Antiarrhythmic With Neurologic Toxicities.

Authors:  Yasmeen M Daraz; Omar H Abdelghffar
Journal:  Cureus       Date:  2022-03-19

2.  Lidocaine-Induced Systemic Toxicity: A Case Report and Review of Literature.

Authors:  Badar Hasan; Talal Asif; Maryam Hasan
Journal:  Cureus       Date:  2017-05-25

3.  The Knowledge of Eye Physicians on Local Anesthetic Toxicity and Intravenous Lipid Treatment: Questionnaire Study.

Authors:  Aykut Urfalıoğlu; Selma Urfalıoğlu; Gözen Öksüz
Journal:  Turk J Ophthalmol       Date:  2017-12-25

4.  Improving local anaesthetic systemic toxicity (LAST) awareness in maternity care using tailored educational tools.

Authors:  Amy E Edwards; Gemma M Bowsher; Sahil Deepak; Mohamed Ali
Journal:  BMJ Open Qual       Date:  2018-04-17
  4 in total

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