Literature DB >> 27909529

Emergency Department Readmission in Elderly Patients After Acute Rhythm or Rate Control Treatment for Atrial Fibrillation.

Bonora Antonio1, Turcato Gianni2, Franchi Elena3, Dilda Alice1, Taioli Gabriele2, Serafini Valentina2, Sivero Valentina2, Zannoni Massimo1, Ricci Giorgio1, Olivieri Oliviero4.   

Abstract

Atrial fibrillation (AF) is an age-related increasing disease, characterized by a high number of relapses frequently leading the patients to Emergency Department (ED). Despite AF relapses may be clinically heterogeneous, a proper management requires either a fast and effective restore of the sinus rhythm or a satisfactory control of the ventricular rate. Whether the strategy adopted in the ED could affect the course of disease is still debated. Therefore, the aim of our study was to evaluate the number of ED readmission for AF related symptoms and the event-free period in patients older than 70 years previously treated in ED for an AF recurrence, in order to assess a possible relationship with the acute strategy. An overall number of 302 recurrences of AF were drawn randomly, regarding 102 patients (mean age 78 years). We found that 206 cases (68.2%) were treated with rhythm restoration strategy (RR) whereas 96 (31.8%) with rate control strategy (RC). The median following event-free period was 118.6 +/- 15.5 and 212.9 +/- 37.1 days (p < 0.05) for RR and RC strategy, respectively. Within 6 months, 124 (60.1%) out of RR group patients and only 44 (45.8%) out of RC group patients had to be readmitted to ED for AF related symptoms (whether a recurrence or inefficient rate control symptoms) (p< 0.05). This advantage was substantially confirmed (79.1% vs 65.6% respectively, p < 0.05) after a 12 months follow-up. Our results indicate that acute treatment of AF may affect the long-term outcome of the disease and the ED readmission rate of the patient. Ventricular rate control seems to be associated with a longer event-free period if compared to the rhythm control strategy in the elderly patients. This suggests an age-based work-up of patients admitted to the ED, preferentially using ventricular rate control in elderly subjects.

Entities:  

Keywords:  Atrial Fibrillation; Rate Control; Recurrences ; Rhythm Control

Year:  2016        PMID: 27909529      PMCID: PMC5129682          DOI: 10.4022/jafib.1387

Source DB:  PubMed          Journal:  J Atr Fibrillation        ISSN: 1941-6911


  32 in total

1.  Comparative effectiveness of rhythm control vs rate control drug treatment effect on mortality in patients with atrial fibrillation.

Authors:  Raluca Ionescu-Ittu; Michal Abrahamowicz; Cynthia A Jackevicius; Vidal Essebag; Mark J Eisenberg; Willy Wynant; Hugues Richard; Louise Pilote
Journal:  Arch Intern Med       Date:  2012-07-09

2.  A comparison of rate control and rhythm control in patients with recurrent persistent atrial fibrillation.

Authors:  Isabelle C Van Gelder; Vincent E Hagens; Hans A Bosker; J Herre Kingma; Otto Kamp; Tsjerk Kingma; Salah A Said; Julius I Darmanata; Alphons J M Timmermans; Jan G P Tijssen; Harry J G M Crijns
Journal:  N Engl J Med       Date:  2002-12-05       Impact factor: 91.245

3.  Progression of atrial fibrillation in the REgistry on Cardiac rhythm disORDers assessing the control of Atrial Fibrillation cohort: clinical correlates and the effect of rhythm-control therapy.

Authors:  Cees B De Vos; Günter Breithardt; A John Camm; Paul Dorian; Peter R Kowey; Jean-Yves Le Heuzey; Lisa Naditch-Brûlé; Eric N Prystowsky; Peter J Schwartz; Christian Torp-Pedersen; William S Weintraub; Harry J Crijns
Journal:  Am Heart J       Date:  2012-05       Impact factor: 4.749

Review 4.  Global epidemiology of atrial fibrillation.

Authors:  Faisal Rahman; Gene F Kwan; Emelia J Benjamin
Journal:  Nat Rev Cardiol       Date:  2014-08-12       Impact factor: 32.419

5.  Estimates of current and future incidence and prevalence of atrial fibrillation in the U.S. adult population.

Authors:  Susan Colilla; Ann Crow; William Petkun; Daniel E Singer; Teresa Simon; Xianchen Liu
Journal:  Am J Cardiol       Date:  2013-07-04       Impact factor: 2.778

Review 6.  Rate or rhythm control for atrial fibrillation: update and controversies.

Authors:  Jason S Chinitz; Jonathan L Halperin; Vivek Y Reddy; Valentin Fuster
Journal:  Am J Med       Date:  2012-08-30       Impact factor: 4.965

7.  Incidence and prevalence of atrial fibrillation and associated mortality among Medicare beneficiaries, 1993-2007.

Authors:  Jonathan P Piccini; Bradley G Hammill; Moritz F Sinner; Paul N Jensen; Adrian F Hernandez; Susan R Heckbert; Emelia J Benjamin; Lesley H Curtis
Journal:  Circ Cardiovasc Qual Outcomes       Date:  2012-01-10

8.  Stroke in paroxysmal atrial fibrillation: report from the Stockholm Cohort of Atrial Fibrillation.

Authors:  Leif Friberg; Niklas Hammar; Mårten Rosenqvist
Journal:  Eur Heart J       Date:  2009-01-27       Impact factor: 29.983

9.  Atrial fibrillation begets atrial fibrillation: autonomic mechanism for atrial electrical remodeling induced by short-term rapid atrial pacing.

Authors:  Zhibing Lu; Benjamin J Scherlag; Jiaxiong Lin; Guodong Niu; Kar-Ming Fung; Lichao Zhao; Muhammad Ghias; Warren M Jackman; Ralph Lazzara; Hong Jiang; Sunny S Po
Journal:  Circ Arrhythm Electrophysiol       Date:  2008-06-23

Review 10.  Epidemiology of atrial fibrillation: European perspective.

Authors:  Massimo Zoni-Berisso; Fabrizio Lercari; Tiziana Carazza; Stefano Domenicucci
Journal:  Clin Epidemiol       Date:  2014-06-16       Impact factor: 4.790

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