Literature DB >> 27909322

Ketamine Mechanism of Action: Separating the Wheat from the Chaff.

Todd D Gould1,2,3, Panos Zanos1, Carlos A Zarate4.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2017        PMID： 27909322      PMCID： PMC5143504          DOI： 10.1038/npp.2016.210

Source DB:  PubMed          Journal:  Neuropsychopharmacology        ISSN： 0893-133X            Impact factor:   7.853


× No keyword cloud information.
  6 in total

1.  What is hydroxynorketamine and what can it bring to neurotherapeutics?

Authors:  Nagendra S Singh; Carlos A Zarate; Ruin Moaddel; Michel Bernier; Irving W Wainer
Journal:  Expert Rev Neurother       Date:  2014-11       Impact factor: 4.618

2.  A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression.

Authors:  Carlos A Zarate; Jaskaran B Singh; Paul J Carlson; Nancy E Brutsche; Rezvan Ameli; David A Luckenbaugh; Dennis S Charney; Husseini K Manji
Journal:  Arch Gen Psychiatry       Date:  2006-08

3.  Stereoselective and regiospecific hydroxylation of ketamine and norketamine.

Authors:  Zeruesenay Desta; Ruin Moaddel; Evan T Ogburn; Cong Xu; Anuradha Ramamoorthy; Swarajya Lakshmi Vattem Venkata; Mitesh Sanghvi; Michael E Goldberg; Marc C Torjman; Irving W Wainer
Journal:  Xenobiotica       Date:  2012-05-21       Impact factor: 1.908

Review 4.  Ketamine and Other NMDA Antagonists: Early Clinical Trials and Possible Mechanisms in Depression.

Authors:  D Jeffrey Newport; Linda L Carpenter; William M McDonald; James B Potash; Mauricio Tohen; Charles B Nemeroff
Journal:  Am J Psychiatry       Date:  2015-10       Impact factor: 18.112

5.  Studies on the biotransformation of ketamine. 1-Identification of metabolites produced in vitro from rat liver microsomal preparations.

Authors:  J D Adams; T A Baillie; A J Trevor; N Castagnoli
Journal:  Biomed Mass Spectrom       Date:  1981-11

6.  NMDAR inhibition-independent antidepressant actions of ketamine metabolites.

Authors:  Panos Zanos; Ruin Moaddel; Patrick J Morris; Polymnia Georgiou; Jonathan Fischell; Greg I Elmer; Manickavasagom Alkondon; Peixiong Yuan; Heather J Pribut; Nagendra S Singh; Katina S S Dossou; Yuhong Fang; Xi-Ping Huang; Cheryl L Mayo; Irving W Wainer; Edson X Albuquerque; Scott M Thompson; Craig J Thomas; Carlos A Zarate; Todd D Gould
Journal:  Nature       Date:  2016-05-04       Impact factor: 49.962
  6 in total
  6 in total

1.  Ketamine for Social Anxiety Disorder: A Randomized, Placebo-Controlled Crossover Trial.

Authors:  Jerome H Taylor; Angeli Landeros-Weisenberger; Catherine Coughlin; Jilian Mulqueen; Jessica A Johnson; Daniel Gabriel; Margot O Reed; Ewgeni Jakubovski; Michael H Bloch
Journal:  Neuropsychopharmacology       Date:  2017-08-29       Impact factor: 7.853

Review 2.  Mechanisms of ketamine and its metabolites as antidepressants.

Authors:  Evan M Hess; Lace M Riggs; Michael Michaelides; Todd D Gould
Journal:  Biochem Pharmacol       Date:  2021-12-27       Impact factor: 5.858

3.  Brain-Wide Mapping of Afferent Inputs to Accumbens Nucleus Core Subdomains and Accumbens Nucleus Subnuclei.

Authors:  Liping Ma; Wenqi Chen; Danfang Yu; Yunyun Han
Journal:  Front Syst Neurosci       Date:  2020-03-18

4.  (R)-Ketamine Induces a Greater Increase in Prefrontal 5-HT Release Than (S)-Ketamine and Ketamine Metabolites via an AMPA Receptor-Independent Mechanism.

Authors:  Yukio Ago; Wataru Tanabe; Momoko Higuchi; Shinji Tsukada; Tatsunori Tanaka; Takumi Yamaguchi; Hisato Igarashi; Rei Yokoyama; Kaoru Seiriki; Atsushi Kasai; Takanobu Nakazawa; Shinsaku Nakagawa; Kenji Hashimoto; Hitoshi Hashimoto
Journal:  Int J Neuropsychopharmacol       Date:  2019-10-01       Impact factor: 5.176

Review 5.  Inflammatory signaling mechanisms in bipolar disorder.

Authors:  Gregory H Jones; Courtney M Vecera; Omar F Pinjari; Rodrigo Machado-Vieira
Journal:  J Biomed Sci       Date:  2021-06-11       Impact factor: 8.410

Review 6.  Positive AMPA receptor modulation in the treatment of neuropsychiatric disorders: A long and winding road.

Authors:  Bashkim Kadriu; Laura Musazzi; Jenessa N Johnston; Lisa E Kalynchuk; Hector J Caruncho; Maurizio Popoli; Carlos A Zarate
Journal:  Drug Discov Today       Date:  2021-08-03       Impact factor: 8.369
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.