[Is the fluorescence cytotoxicity test for the determination of HLA-DR antigens more sensitive than the classical microcytotoxicity test?].

The authors compare the sensitivity of the testing methods for determining HLA-DR antigens on B-lymphocytes and monocytes (classical eosin technique) with the fluorescence cytotoxic tests (FCT). The assessment of results of DR specificity determination in blood donors and patients with blood disease showed comparability of the tests. The rate of concordance ranged from 88-89%. The paper discusses the advantages and disadvantages of each method.