Literature DB >> 27908518

Gastrointestinal Angiodysplasia: Diagnosis and Management.

Christian S Jackson1, Richard Strong2.   

Abstract

Gastrointestinal angiodysplasia (GIAD) are red flat arborized lesions that are found throughout the entire gastrointestinal tract. GIAD can vary in size and have a range of presentation from occult to life-threatening bleeding. The typical presentation is intermittent bleeding in the setting of iron deficiency anemia. Endoscopy is the primary means of diagnosis and endoscopic therapy is noted to be initially effective. However, rebleeding can be as high as 40% to 50% in patients with small bowel GIAD. This review describes the pathophysiology for the development of GIAD and the current roles of endoscopic, medical, and surgical therapy in its treatment. Published by Elsevier Inc.

Entities:  

Keywords:  Anti-angiogenic therapy; Capsule endoscopy; Deep enteroscopy; Gastrointestinal angiodysplasia; Rebleeding; Vascular endothelial growth factor

Mesh:

Year:  2017        PMID: 27908518     DOI: 10.1016/j.giec.2016.08.012

Source DB:  PubMed          Journal:  Gastrointest Endosc Clin N Am        ISSN: 1052-5157


  5 in total

1.  Bevacizumab for Refractory Gastrointestinal Bleeding in Rendu-Osler-Weber Disease.

Authors:  Carlos Bernardes; Sara Santos; Rafaela Loureiro; Verónica Borges; Gonçalo Ramos
Journal:  GE Port J Gastroenterol       Date:  2017-10-05

2.  Diagnosis and treatment of malignant-appearing arteriovenous malformation.

Authors:  Rebekah John; Gurkarminder Sandhu; Christopher Naumann
Journal:  Proc (Bayl Univ Med Cent)       Date:  2021-02-05

Review 3.  Leptin and Obesity: Role and Clinical Implication.

Authors:  Milan Obradovic; Emina Sudar-Milovanovic; Sanja Soskic; Magbubah Essack; Swati Arya; Alan J Stewart; Takashi Gojobori; Esma R Isenovic
Journal:  Front Endocrinol (Lausanne)       Date:  2021-05-18       Impact factor: 5.555

4.  Thalidomide targets EGFL6 to inhibit EGFL6/PAX6 axis-driven angiogenesis in small bowel vascular malformation.

Authors:  Chao-Tao Tang; Qing-Wei Zhang; Shan Wu; Ming-Yu Tang; Qian Liang; Xiao-Lu Lin; Yun-Jie Gao; Zhi-Zheng Ge
Journal:  Cell Mol Life Sci       Date:  2020-02-01       Impact factor: 9.261

Review 5.  Scoring systems in clinical small-bowel capsule endoscopy: all you need to know!

Authors:  Bruno Rosa; Reuma Margalit-Yehuda; Kelly Gatt; Martina Sciberras; Carlo Girelli; Jean-Christophe Saurin; Pablo Cortegoso Valdivia; Jose Cotter; Rami Eliakim; Flavio Caprioli; Gunnar Baatrup; Martin Keuchel; Pierre Ellul; Ervin Toth; Anastasios Koulaouzidis
Journal:  Endosc Int Open       Date:  2021-05-27
  5 in total

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