Literature DB >> 27904982

Magnetic resonance evaluation of cardiac thrombi and masses by T1 and T2 mapping: an observational study.

Thibault Caspar1,2, Soraya El Ghannudi3,4, Mickaël Ohana3,4, Aïssam Labani3, Aubrietia Lawson5, Patrick Ohlmann5, Olivier Morel5, Michel De Mathelin4, Catherine Roy3, Afshin Gangi3,4, Philippe Germain3.   

Abstract

The purpose of this work was to evaluate CMR T1 and T2 mapping sequences in patients with intracardiac thrombi and masses in order to assess T1 and T2 relaxometry usefulness and to allow better etiological diagnosis. This observational study of patients scheduled for routine CMR was performed from September 2014 to August 2015. All patients referred to our department for a 1.5 T CMR were screened to participate. T1 mapping were acquired before and after Gadolinium injection; T2 mapping images were obtained before injection. 41 patients were included. 22 presented with cardiac thrombi and 19 with cardiac masses. The native T1 of thrombi was 1037 ± 152 ms (vs 1032 ± 39 ms for myocardium, p = 0.88; vs 1565 ± 88 ms for blood pool, p < 0.0001). T2 were 74 ± 13 ms (vs 51 ± 3 ms for myocardium, p < 0.0001; vs 170 ± 32 ms for blood pool, p < 0.0001). Recent thrombi had a native T1 shorter than old thrombi (911 ± 177 vs 1169 ± 107 ms, p = 0.01). The masses having a shorter T1 than the myocardium were lipomas (278 ± 29 ms), calcifications (621 ± 218 ms), and melanoma (736 ms). All other masses showed T1 values higher than myocardial T1, with T2 consistently >70 ms. T1 and T2 mapping CMR sequences can be useful and represent a new approach for the evaluation of cardiac thrombi and masses.

Entities:  

Keywords:  Cardiac imaging techniques; Cardiac tumors; Heart neoplasms; Magnetic resonance imaging; Thrombus

Mesh:

Substances:

Year:  2016        PMID: 27904982     DOI: 10.1007/s10554-016-1034-6

Source DB:  PubMed          Journal:  Int J Cardiovasc Imaging        ISSN: 1569-5794            Impact factor:   2.357


  18 in total

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