Literature DB >> 2790474

Behavioral characteristics of the SAM-P/8 strain in Sidman active avoidance task.

A Ohta1, T Hirano, H Yagi, S Tanaka, M Hosokawa, T Takeda.   

Abstract

The behavior of the senescence-accelerated mouse (SAM-P/8) at the age of 1, 2, 4 and 10-11 months in Sidman active avoidance learning was analyzed, and compared to findings in the controls (SAM-R/1). At the age of 1 and 2 months, learning was comparable in these two strains. At the age of 4 and 10-11 months, SAM-P/8 but not SAM-R/1 learned active avoidance. We propose that SAM-P/8 can serve as a valid model of deficits in learning and memory.

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Year:  1989        PMID： 2790474     DOI： 10.1016/0006-8993(89)90421-6

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  9 in total

1.  Free radical oxidation of brain proteins in accelerated senescence and its modulation by N-tert-butyl-alpha-phenylnitrone.

Authors:  D A Butterfield; B J Howard; S Yatin; K L Allen; J M Carney
Journal:  Proc Natl Acad Sci U S A       Date:  1997-01-21       Impact factor: 11.205

Review 2.  Mechanisms of oxidative stress resistance in the brain: Lessons learned from hypoxia tolerant extremophilic vertebrates.

Authors:  Valentina R Garbarino; Miranda E Orr; Karl A Rodriguez; Rochelle Buffenstein
Journal:  Arch Biochem Biophys       Date:  2015-04-01       Impact factor: 4.013

3.  Monoamine oxidase-B-positive granular structures in the hippocampus of aged senescence-accelerated mouse (SAMP8).

Authors:  S Nakamura; I Akiguchi; N Seriu; K Ohnishi; M Takemura; M Ueno; H Tomimoto; T Kawamata; J Kimura; M Hosokawa
Journal:  Acta Neuropathol       Date:  1995       Impact factor: 17.088

4.  Beta/A4 proteinlike immunoreactive granular structures in the brain of senescence-accelerated mouse.

Authors:  M Takemura; S Nakamura; I Akiguchi; M Ueno; N Oka; S Ishikawa; A Shimada; J Kimura; T Takeda
Journal:  Am J Pathol       Date:  1993-06       Impact factor: 4.307

Review 5.  Senescence-accelerated mouse (SAM) with special references to neurodegeneration models, SAMP8 and SAMP10 mice.

Authors:  Toshio Takeda
Journal:  Neurochem Res       Date:  2009-02-07       Impact factor: 3.996

6.  Enriched environment and masticatory activity rehabilitation recover spatial memory decline in aged mice.

Authors:  Fabíola de Carvalho Chaves de Siqueira Mendes; Marina Negrão Frota de Almeida; André Pinheiro Gurgel Felício; Ana Carla Fadel; Diego de Jesus Silva; Thaíssa Gomes Borralho; Rodrigo Perez da Silva; João Bento-Torres; Pedro Fernando da Costa Vasconcelos; Victor Hugh Perry; Edson Marcos Leal Soares Ramos; Cristovam Wanderley Picanço-Diniz; Marcia Consentino Kronka Sosthenes
Journal:  BMC Neurosci       Date:  2013-06-28       Impact factor: 3.288

7.  Motor Dyscoordination and Alteration of Functional Correlation Between DGKγ and PKCγ in Senescence-Accelerated Mouse Prone 8 (SAMP8).

Authors:  Ryosuke Tsumagari; Kenta Maruo; Takaaki Nakao; Shuji Ueda; Minoru Yamanoue; Yasuhito Shirai
Journal:  Front Aging Neurosci       Date:  2021-01-28       Impact factor: 5.750

8.  Sedentary Life and Reduced Mastication Impair Spatial Learning and Memory and Differentially Affect Dentate Gyrus Astrocyte Subtypes in the Aged Mice.

Authors:  Fabíola de Carvalho Chaves de Siqueira Mendes; Luisa Taynah Vasconcelos Barbosa Paixão; Daniel Guerreiro Diniz; Daniel Clive Anthony; Dora Brites; Cristovam Wanderley Picanço Diniz; Marcia Consentino Kronka Sosthenes
Journal:  Front Neurosci       Date:  2021-04-15       Impact factor: 4.677

Review 9.  Characterization of senescence-accelerated mouse prone 6 (SAMP6) as an animal model for brain research.

Authors:  Kimie Niimi; Eiki Takahashi
Journal:  Exp Anim       Date:  2014
  9 in total

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