Literature DB >> 2789932

Yohimbine increases human salivary secretion.

E Chatelut1, Y Rispail, M Berlan, J L Montastruc.   

Abstract

The effect of oral yohimbine (14 mg) on salivary secretion was evaluated in healthy volunteers. Yohimbine significantly increased salivary secretion when compared with placebo. This effect was significant from 60 min until 180 min after administration under our experimental conditions. Yohimbine (or alpha 2-adrenoceptor blocking agents) could have a potential interest in the treatment of dry mouths.

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Year:  1989        PMID： 2789932      PMCID： PMC1379958          DOI： 10.1111/j.1365-2125.1989.tb05440.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  6 in total

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Authors:  M Taouis; M Berlan; P Montastruc; M Lafontan
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2.  Alpha 2-antagonist compounds and lipid mobilization: evidence for a lipid mobilizing effect of oral yohimbine in healthy male volunteers.

Authors:  J Galitzky; M Taouis; M Berlan; D Rivière; M Garrigues; M Lafontan
Journal:  Eur J Clin Invest       Date:  1988-12       Impact factor: 4.686

3.  Distribution and metabolism of tritiated yohimbine in mice.

Authors:  A K Ho; D B Hoffman; S Gershon; H H Loh
Journal:  Arch Int Pharmacodyn Ther       Date:  1971-12

4.  The mechanism of the clonidine-induced reduction in peripheral parasympathetic submaxillary salivation.

Authors:  G J Green; H Wilson; M S Yates
Journal:  Eur J Pharmacol       Date:  1979-07-01       Impact factor: 4.432

5.  The pharmacokinetics of yohimbine in man.

Authors:  J A Owen; S L Nakatsu; J Fenemore; M Condra; D H Surridge; A Morales
Journal:  Eur J Clin Pharmacol       Date:  1987       Impact factor: 2.953

6.  The pharmacokinetic properties of yohimbine in the conscious rat.

Authors:  J W Hubbard; S L Pfister; A M Biediger; T C Herzig; T K Keeton
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1988-05       Impact factor: 3.000
  6 in total
  10 in total

1.  Effect of 3 weeks treatment with yohimbine on salivary secretion in healthy volunteers and in depressed patients treated with tricyclic antidepressants.

Authors:  H Bagheri; L Schmitt; M Berlan; J L Montastruc
Journal:  Br J Clin Pharmacol       Date:  1992-12       Impact factor: 4.335

2.  Yohimbine increases salivary secretion in depressed patients treated with tricyclic antidepressants.

Authors:  Y Rispail; L Schmitt; M Berlan; J L Montastruc; P Montastruc
Journal:  Eur J Clin Pharmacol       Date:  1990       Impact factor: 2.953

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4.  Yohimbine and lacrimal secretion.

Authors:  H Bagheri; M Berlan; J L Montastruc; P Montastruc
Journal:  Br J Clin Pharmacol       Date:  1990-07       Impact factor: 4.335

5.  Pharmacodynamic effects of chronic yohimbine treatment in healthy volunteers.

Authors:  J Galitzky; D Rivière; M A Tran; J L Montastruc; M Berlan
Journal:  Eur J Clin Pharmacol       Date:  1990       Impact factor: 2.953

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7.  Yohimbine increases submaxillary kallikrein release into the saliva in dogs: evidence for alpha 2-adrenoceptor-mediated inhibition of cholinergic pathways.

Authors:  J P Girolami; J L Bascands; C Pécher; M Berlan; J L Montastruc; P Montastruc
Journal:  Br J Pharmacol       Date:  1991-02       Impact factor: 8.739

8.  Pharmacokinetic study of yohimbine and its pharmacodynamic effects on salivary secretion in patients treated with tricyclic antidepressants.

Authors:  H Bagheri; P Picault; L Schmitt; G Houin; M Berlan; J L Montastruc
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9.  Effects of physiological and pharmacological variation of sympathetic nervous system activity on plasma non-esterified fatty acid concentrations in man.

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Review 10.  Gastrointestinal Dysfunctions in Parkinson's Disease: Symptoms and Treatments.

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  10 in total

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