Literature DB >> 27896967

METHODS TO ENSURE THE REPRODUCIBILITY OF BIOMEDICAL RESEARCH.

Konrad J Karczewski1, Nicholas P Tatonetti, Arjun K Manrai, Chirag J Patel, C Titus Brown, John P A Ioannidis.   

Abstract

Science is not done in a vacuum - across fields of biomedicine, scientists have built on previous research and used data published in previous papers. A mainstay of scientific inquiry is the publication of one's research and recognition for this work is given in the form of citations and notoriety - ideally given in proportion to the quality of the work. Academic incentives, however, may encourage individual researchers to prioritize career ambitions over scientific truth. Recently, the New England Journal of Medicine published a commentary calling scientists who repurpose data "research parasites" who misuse data generated by others to demonstrate alternative hypotheses. In our opinion, the concept of data hoarding not only runs contrary to the spirit of, but also hinders scientific progress. Scientific research is meant to seek objective truth, rather than promote a personal agenda, and the only way to do so is through maximum transparency and reproducibility, no matter who is using the data….

Entities:  

Year:  2017        PMID: 27896967      PMCID: PMC5984201          DOI: 10.1142/9789813207813_0012

Source DB:  PubMed          Journal:  Pac Symp Biocomput        ISSN: 2335-6928


  12 in total

1.  Data Sharing.

Authors:  Dan L Longo; Jeffrey M Drazen
Journal:  N Engl J Med       Date:  2016-01-21       Impact factor: 91.245

2.  Scaling metagenome sequence assembly with probabilistic de Bruijn graphs.

Authors:  Jason Pell; Arend Hintze; Rosangela Canino-Koning; Adina Howe; James M Tiedje; C Titus Brown
Journal:  Proc Natl Acad Sci U S A       Date:  2012-07-30       Impact factor: 11.205

3.  DATA SHARING AND REPRODUCIBLE CLINICAL GENETIC TESTING: SUCCESSES AND CHALLENGES.

Authors:  Shan Yang; Melissa Cline; Can Zhang; Benedict Paten; Stephen E Lincoln
Journal:  Pac Symp Biocomput       Date:  2017

4.  EXPLORING THE REPRODUCIBILITY OF PROBABILISTIC CAUSAL MOLECULAR NETWORK MODELS.

Authors:  Ariella Cohain; Aparna A Divaraniya; Kuixi Zhu; Joseph R Scarpa; Andrew Kasarskis; Jun Zhu; Rui Chang; Joel T Dudley; Eric E Schadt
Journal:  Pac Symp Biocomput       Date:  2017

5.  EMPOWERING MULTI-COHORT GENE EXPRESSION ANALYSIS TO INCREASE REPRODUCIBILITY.

Authors:  Winston A Haynes; Francesco Vallania; Charles Liu; Erika Bongen; Aurelie Tomczak; Marta Andres-Terrè; Shane Lofgren; Andrew Tam; Cole A Deisseroth; Matthew D Li; Timothy E Sweeney; Purvesh Khatri
Journal:  Pac Symp Biocomput       Date:  2017

6.  Quantifying prion disease penetrance using large population control cohorts.

Authors:  Eric Vallabh Minikel; Sonia M Vallabh; Monkol Lek; Karol Estrada; Kaitlin E Samocha; J Fah Sathirapongsasuti; Cory Y McLean; Joyce Y Tung; Linda P C Yu; Pierluigi Gambetti; Janis Blevins; Shulin Zhang; Yvonne Cohen; Wei Chen; Masahito Yamada; Tsuyoshi Hamaguchi; Nobuo Sanjo; Hidehiro Mizusawa; Yosikazu Nakamura; Tetsuyuki Kitamoto; Steven J Collins; Alison Boyd; Robert G Will; Richard Knight; Claudia Ponto; Inga Zerr; Theo F J Kraus; Sabina Eigenbrod; Armin Giese; Miguel Calero; Jesús de Pedro-Cuesta; Stéphane Haïk; Jean-Louis Laplanche; Elodie Bouaziz-Amar; Jean-Philippe Brandel; Sabina Capellari; Piero Parchi; Anna Poleggi; Anna Ladogana; Anne H O'Donnell-Luria; Konrad J Karczewski; Jamie L Marshall; Michael Boehnke; Markku Laakso; Karen L Mohlke; Anna Kähler; Kimberly Chambert; Steven McCarroll; Patrick F Sullivan; Christina M Hultman; Shaun M Purcell; Pamela Sklar; Sven J van der Lee; Annemieke Rozemuller; Casper Jansen; Albert Hofman; Robert Kraaij; Jeroen G J van Rooij; M Arfan Ikram; André G Uitterlinden; Cornelia M van Duijn; Mark J Daly; Daniel G MacArthur
Journal:  Sci Transl Med       Date:  2016-01-20       Impact factor: 17.956

7.  Software Carpentry: lessons learned.

Authors:  Greg Wilson
Journal:  F1000Res       Date:  2014-02-19

8.  How to make more published research true.

Authors:  John P A Ioannidis
Journal:  PLoS Med       Date:  2014-10-21       Impact factor: 11.069

9.  These are not the k-mers you are looking for: efficient online k-mer counting using a probabilistic data structure.

Authors:  Qingpeng Zhang; Jason Pell; Rosangela Canino-Koning; Adina Chuang Howe; C Titus Brown
Journal:  PLoS One       Date:  2014-07-25       Impact factor: 3.240

10.  Analysis of protein-coding genetic variation in 60,706 humans.

Authors:  Monkol Lek; Konrad J Karczewski; Eric V Minikel; Kaitlin E Samocha; Eric Banks; Timothy Fennell; Anne H O'Donnell-Luria; James S Ware; Andrew J Hill; Beryl B Cummings; Taru Tukiainen; Daniel P Birnbaum; Jack A Kosmicki; Laramie E Duncan; Karol Estrada; Fengmei Zhao; James Zou; Emma Pierce-Hoffman; Joanne Berghout; David N Cooper; Nicole Deflaux; Mark DePristo; Ron Do; Jason Flannick; Menachem Fromer; Laura Gauthier; Jackie Goldstein; Namrata Gupta; Daniel Howrigan; Adam Kiezun; Mitja I Kurki; Ami Levy Moonshine; Pradeep Natarajan; Lorena Orozco; Gina M Peloso; Ryan Poplin; Manuel A Rivas; Valentin Ruano-Rubio; Samuel A Rose; Douglas M Ruderfer; Khalid Shakir; Peter D Stenson; Christine Stevens; Brett P Thomas; Grace Tiao; Maria T Tusie-Luna; Ben Weisburd; Hong-Hee Won; Dongmei Yu; David M Altshuler; Diego Ardissino; Michael Boehnke; John Danesh; Stacey Donnelly; Roberto Elosua; Jose C Florez; Stacey B Gabriel; Gad Getz; Stephen J Glatt; Christina M Hultman; Sekar Kathiresan; Markku Laakso; Steven McCarroll; Mark I McCarthy; Dermot McGovern; Ruth McPherson; Benjamin M Neale; Aarno Palotie; Shaun M Purcell; Danish Saleheen; Jeremiah M Scharf; Pamela Sklar; Patrick F Sullivan; Jaakko Tuomilehto; Ming T Tsuang; Hugh C Watkins; James G Wilson; Mark J Daly; Daniel G MacArthur
Journal:  Nature       Date:  2016-08-18       Impact factor: 49.962

View more
  3 in total

1.  Considerations for an integrated population health databank in Africa: lessons from global best practices.

Authors:  Jude O Igumbor; Edna N Bosire; Marta Vicente-Crespo; Ehimario U Igumbor; Uthman A Olalekan; Tobias F Chirwa; Sam M Kinyanjui; Catherine Kyobutungi; Sharon Fonn
Journal:  Wellcome Open Res       Date:  2021-08-23

Review 2.  What incentives increase data sharing in health and medical research? A systematic review.

Authors:  Anisa Rowhani-Farid; Michelle Allen; Adrian G Barnett
Journal:  Res Integr Peer Rev       Date:  2017-05-05

3.  Assessment of the impact of EHR heterogeneity for clinical research through a case study of silent brain infarction.

Authors:  Sunyang Fu; Lester Y Leung; Anne-Olivia Raulli; David F Kallmes; Kristin A Kinsman; Kristoff B Nelson; Michael S Clark; Patrick H Luetmer; Paul R Kingsbury; David M Kent; Hongfang Liu
Journal:  BMC Med Inform Decis Mak       Date:  2020-03-30       Impact factor: 2.796

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.