Literature DB >> 27896438

Survival of a recessive allele in a Mendelian diploid model.

Rebecca Neukirch1, Anton Bovier2.   

Abstract

In this paper we analyse the genetic evolution of a diploid hermaphroditic population, which is modelled by a three-type nonlinear birth-and-death process with competition and Mendelian reproduction. In a recent paper, Collet et al. (J Math Biol 67(3):569-607, 2013) have shown that, on the mutation time-scale, the process converges to the Trait-Substitution Sequence of adaptive dynamics, stepping from one homozygotic state to another with higher fitness. We prove that, under the assumption that a dominant allele is also the fittest one, the recessive allele survives for a time of order at least [Formula: see text], where K is the size of the population and [Formula: see text].

Entities:  

Keywords:  Adaptive dynamics; Diploid population; Genetic variability; Mendelian reproduction; Nonlinear birth-and-death process; Population genetics

Mesh:

Year:  2016        PMID: 27896438     DOI: 10.1007/s00285-016-1081-6

Source DB:  PubMed          Journal:  J Math Biol        ISSN: 0303-6812            Impact factor:   2.259


  7 in total

1.  Evolution in Mendelian Populations.

Authors:  S Wright
Journal:  Genetics       Date:  1931-03       Impact factor: 4.562

2.  How should we define 'fitness' for general ecological scenarios?

Authors:  J A Metz; R M Nisbet; S A Geritz
Journal:  Trends Ecol Evol       Date:  1992-06       Impact factor: 17.712

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Authors:  U Dieckmann; R Law
Journal:  J Math Biol       Date:  1996       Impact factor: 2.259

4.  Slow-fast stochastic diffusion dynamics and quasi-stationarity for diploid populations with varying size.

Authors:  Camille Coron
Journal:  J Math Biol       Date:  2015-04-04       Impact factor: 2.259

5.  ADAPTIVE DYNAMICS IN ALLELE SPACE: EVOLUTION OF GENETIC POLYMORPHISM BY SMALL MUTATIONS IN A HETEROGENEOUS ENVIRONMENT.

Authors:  Éva Kisdi; Stefan A H Geritz
Journal:  Evolution       Date:  1999-08       Impact factor: 3.694

6.  A rigorous model study of the adaptive dynamics of Mendelian diploids.

Authors:  Pierre Collet; Sylvie Méléard; Johan A J Metz
Journal:  J Math Biol       Date:  2012-07-21       Impact factor: 2.259

7.  Quantifying the mutational meltdown in diploid populations.

Authors:  Camille Coron; Sylvie Méléard; Emmanuelle Porcher; Alexandre Robert
Journal:  Am Nat       Date:  2013-05       Impact factor: 3.926

  7 in total
  3 in total

1.  From adaptive dynamics to adaptive walks.

Authors:  Anna Kraut; Anton Bovier
Journal:  J Math Biol       Date:  2019-07-26       Impact factor: 2.259

2.  A stochastic model for speciation by mating preferences.

Authors:  Camille Coron; Manon Costa; Hélène Leman; Charline Smadi
Journal:  J Math Biol       Date:  2017-09-15       Impact factor: 2.259

3.  The recovery of a recessive allele in a Mendelian diploid model.

Authors:  Anton Bovier; Loren Coquille; Rebecca Neukirch
Journal:  J Math Biol       Date:  2018-05-08       Impact factor: 2.259

  3 in total

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