Literature DB >> 27895451

Non-cardiogenic pulmonary edema, rhabdomyolysis and myocardial injury following heroin inhalation: a case report.

G Bazoukis1, A Spiliopoulou1, K Mourouzis1, P Grigoropoulou1, A Yalouris1.   

Abstract

BACKGROUND: Heroin use by non-injecting routes of administration (snorting, swallowing, "chasing the dragon") is considered to be safer but is not risk-free for fatal overdose or serious side effects. We report the case of an adolescent who was transferred unconscious to the emergency department after heroin inhalation. Description of the case: A 17-year-old male was transferred to the emergency department unconscious (Glasgow coma scale: 6/15) after heroin inhalation. He was treated with non-rebreather mask and intravenous infusion of naloxone with gradual improvement of consciousness and arterial blood gasses. The chest computed tomography showed signs of acute respiratory distress syndrome. Laboratory exams on the second day of hospitalization showed elevated creatine kinase (CK) and troponin-I levels while his electrocardiography (ECG) showed J-point elevation in V1, V2, and V3 precordial leads. On the second day of hospitalization the pulmonary infiltrates were not present in his chest X-ray while on the eighth day, troponin-I and CK levels were normalized without dynamic ECG changes and the patient was discharged uneventfully.
CONCLUSION: Heroin inhalation may cause severe complications, such as non-cardiogenic pulmonary edema, rhabdomyolysis or myocardial injury. Hippokratia 2016, 20(1): 84-87.

Entities:  

Keywords:  Heroin inhalation; heroin; illegal drugs; non-cardiogenic pulmonary edema; rhabdomyolysis

Year:  2016        PMID: 27895451      PMCID: PMC5074406     

Source DB:  PubMed          Journal:  Hippokratia        ISSN: 1108-4189            Impact factor:   0.471


  20 in total

Review 1.  Naloxone in opioid poisoning: walking the tightrope.

Authors:  S F J Clarke; P I Dargan; A L Jones
Journal:  Emerg Med J       Date:  2005-09       Impact factor: 2.740

2.  Inhaled heroin causing a life-threatening asthma exacerbation and marked peripheral eosinophilia.

Authors:  Christopher I Whale; Andrew W Molyneux; Michael J Ward
Journal:  Br J Hosp Med (Lond)       Date:  2007-06       Impact factor: 0.825

3.  Fatal heroin overdoses resulting from non-injecting routes of administration, NSW, Australia, 1992-1996.

Authors:  S Darke; J Ross
Journal:  Addiction       Date:  2000-04       Impact factor: 6.526

4.  Heroin-related noncardiogenic pulmonary edema : a case series.

Authors:  K A Sporer; E Dorn
Journal:  Chest       Date:  2001-11       Impact factor: 9.410

5.  The Association Between Heroin Inhalation and Early Onset Emphysema.

Authors:  Paul P Walker; Erica Thwaite; Suzanne Amin; John M Curtis; Peter M A Calverley
Journal:  Chest       Date:  2015-11       Impact factor: 9.410

6.  Heroin smoking by 'chasing the dragon': origins and history.

Authors:  J Strang; P Griffiths; M Gossop
Journal:  Addiction       Date:  1997-06       Impact factor: 6.526

Review 7.  The large spectrum of pulmonary complications following illicit drug use: features and mechanisms.

Authors:  Bruno Mégarbane; Lucie Chevillard
Journal:  Chem Biol Interact       Date:  2013-10-18       Impact factor: 5.192

8.  High prevalence of hepatitis C virus infection among noninjecting drug users: association with sharing the inhalation implements of crack.

Authors:  Juan Macías; Rosa B Palacios; Evangelina Claro; Julio Vargas; Salvador Vergara; José A Mira; Nicolás Merchante; Juan E Corzo; Juan A Pineda
Journal:  Liver Int       Date:  2008-07       Impact factor: 5.828

9.  Fatal intoxication as a consequence of intranasal administration (snorting) or pulmonary inhalation (smoking) of heroin.

Authors:  I Thiblin; S Eksborg; A Petersson; A Fugelstad; J Rajs
Journal:  Forensic Sci Int       Date:  2004-01-28       Impact factor: 2.395

10.  Nontraumatic rhabdomyolysis with short-term alcohol intoxication - a case report.

Authors:  Stamatis S Papadatos; Georgios Deligiannis; George Bazoukis; Paschalia Michelongona; Aikaterini Spiliopoulou; Stefanos Mylonas; Christos Zissis
Journal:  Clin Case Rep       Date:  2015-08-20
View more
  1 in total

1.  Opioid antidote induced pulmonary edema and lung injury.

Authors:  Keerthi Yarlagadda; Jinah Kim; Tejaswi Kanderi; Selin Sendil; Vinod Kumar Nookala
Journal:  Respir Med Case Rep       Date:  2020-05-29
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.