Zhang Wentao1, Guangyu Lei2, Yang Liu3, Wei Wang2, Tao Song1, Jinzhu Fan1. 1. Department of Orthopedics, Hong Hui Hospital, Xi'an Jiaotong University College of Medicine, Shaanxi 710054, China. 2. Department of Orthopedics, Weinan Central Hospital, Shaanxi 710054, China. 3. Department of Orthopedics, Hong Hui Hospital, Xi'an Jiaotong University College of Medicine, Shaanxi 710054, China. Electronic address: erica.star80@gmail.com.
Abstract
BACKGROUND: To reduce the incidence of osteomyelitis infection, local antibiotic impregnated delivery systems are commonly used as a promising and effective approach to deliver high antibiotic concentrations at the infection site. OBJECTIVE: The objective of this review was to provide a literature review regarding approach to osteomyelitis treatment with antibiotic loaded PMMA. STUDY DESIGN: Literature study regarding osteomyelitis treatment with antibiotic loaded carriers using key terms Antibiotic, osteomyelitis, biodegradable PMMA through published articles. Hands searching of bibliographies of identified articles were also undertaken. CONCLUSION: We concluded that Antibiotic-impregnated PMMA beads are useful options for the treatment of osteomyelitis for prolonged drug therapy.
BACKGROUND: To reduce the incidence of osteomyelitis infection, local antibiotic impregnated delivery systems are commonly used as a promising and effective approach to deliver high antibiotic concentrations at the infection site. OBJECTIVE: The objective of this review was to provide a literature review regarding approach to osteomyelitis treatment with antibiotic loaded PMMA. STUDY DESIGN: Literature study regarding osteomyelitis treatment with antibiotic loaded carriers using key terms Antibiotic, osteomyelitis, biodegradable PMMA through published articles. Hands searching of bibliographies of identified articles were also undertaken. CONCLUSION: We concluded that Antibiotic-impregnated PMMA beads are useful options for the treatment of osteomyelitis for prolonged drug therapy.
Authors: Devin Sindeldecker; Kelly Moore; Anthony Li; Daniel J Wozniak; Matthew Anderson; Devendra H Dusane; Paul Stoodley Journal: Antimicrob Agents Chemother Date: 2020-08-20 Impact factor: 5.191
Authors: C Kreis; F K Aschenbrenner; D Günther; N Tholema-Hans; J Koeppe; S B Rosslenbroich; M J Raschke; T Fuchs Journal: Sci Rep Date: 2022-03-10 Impact factor: 4.996