Literature DB >> 27894492

Management of Trauma-Induced Coagulopathy with Thrombelastography.

Eduardo Gonzalez1, Ernest E Moore2, Hunter B Moore1.   

Abstract

Viscoelastic assays, such as thrombelastography (TEG) and rotational thrombelastometry (ROTEM), have emerged as point-of-care tools that can guide the hemostatic resuscitation of bleeding injured patients. This article describes the role of TEG in contemporary trauma care by explaining this assay's methodology, clinical applications, and result interpretation through description of supporting studies to provide the reader with an evidence-based user's guide. Although TEG and ROTEM are assays based on the same viscoelastic principle, this article is focused on data supporting the use of TEG in trauma, because it is available in trauma centers in North America; ROTEM is mostly available in Europe. Copyright Â
© 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Coagulopathy; Fibrinolysis; Resuscitation; TEG; Thrombelastography; Transfusion

Mesh:

Year:  2017        PMID: 27894492      PMCID: PMC5142763          DOI: 10.1016/j.ccc.2016.09.002

Source DB:  PubMed          Journal:  Crit Care Clin        ISSN: 0749-0704            Impact factor:   3.598


  55 in total

1.  Early coagulopathy predicts mortality in trauma.

Authors:  Jana B A MacLeod; Mauricio Lynn; Mark G McKenney; Stephen M Cohn; Mary Murtha
Journal:  J Trauma       Date:  2003-07

2.  Use of fibrinogen concentrate in bleeding patients.

Authors:  J Montupil; C Carlier; P Van der Linden
Journal:  Anaesthesia       Date:  2015-11       Impact factor: 6.955

3.  Increasing trauma deaths in the United States.

Authors:  Peter Rhee; Bellal Joseph; Viraj Pandit; Hassan Aziz; Gary Vercruysse; Narong Kulvatunyou; Randall S Friese
Journal:  Ann Surg       Date:  2014-07       Impact factor: 12.969

4.  Effects of coagulation factor deficiency on plasma coagulation kinetics determined via thrombelastography: critical roles of fibrinogen and factors II, VII, X and XII.

Authors:  V G Nielsen; B M Cohen; E Cohen
Journal:  Acta Anaesthesiol Scand       Date:  2005-02       Impact factor: 2.105

5.  Changes in blood coagulation.

Authors:  K N Von Kaulla; H Kaye; E von Kaulla; T L Marchioro; T E Starzl
Journal:  Arch Surg       Date:  1966-01

6.  Trauma. Accidental and intentional injuries account for more years of life lost in the U.S. than cancer and heart disease. Among the prescribed remedies are improved preventive efforts, speedier surgery and further research.

Authors:  D D Trunkey
Journal:  Sci Am       Date:  1983-08       Impact factor: 2.142

7.  Rapid thrombelastography delivers real-time results that predict transfusion within 1 hour of admission.

Authors:  Bryan A Cotton; Gabriel Faz; Quinton M Hatch; Zayde A Radwan; Jeanette Podbielski; Charles Wade; Rosemary A Kozar; John B Holcomb
Journal:  J Trauma       Date:  2011-08

8.  Fibrinolysis greater than 3% is the critical value for initiation of antifibrinolytic therapy.

Authors:  Michael P Chapman; Ernest E Moore; Christopher R Ramos; Arsen Ghasabyan; Jeffrey N Harr; Theresa L Chin; John R Stringham; Angela Sauaia; Christopher C Silliman; Anirban Banerjee
Journal:  J Trauma Acute Care Surg       Date:  2013-12       Impact factor: 3.313

9.  Technical report: analysis of citrated blood with thromboelastography: comparison with fresh blood samples.

Authors:  Marcin Wasowicz; Coimbatore Srinivas; Massimiliano Meineri; Brie Banks; Stuart A McCluskey; Keyvan Karkouti
Journal:  Can J Anaesth       Date:  2008-05       Impact factor: 5.063

10.  Hyperfibrinolysis at admission is an uncommon but highly lethal event associated with shock and prehospital fluid administration.

Authors:  Bryan A Cotton; John A Harvin; Vadim Kostousouv; Kristin M Minei; Zayde A Radwan; Herbert Schöchl; Charles E Wade; John B Holcomb; Nena Matijevic
Journal:  J Trauma Acute Care Surg       Date:  2012-08       Impact factor: 3.313

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  31 in total

Review 1.  Hemicorporectomy as a life-saving strategy for severe pelvic ring crush injury: a case report.

Authors:  Salin Pereira Warr; Paula M Jaramillo; Sebastian Tobon Franco; Carlos Oliver Valderrama-Molina; Alfredo Constain Franco
Journal:  Eur J Orthop Surg Traumatol       Date:  2018-02-10

2.  Prospective assessment of fibrinolysis in morbid obesity: tissue plasminogen activator resistance improves after bariatric surgery.

Authors:  Jason Samuels; Peter J Lawson; Alexander P Morton; Hunter B Moore; Kirk C Hansen; Angela Sauaia; Jonathan A Schoen
Journal:  Surg Obes Relat Dis       Date:  2019-04-10       Impact factor: 4.734

3.  The use of viscoelastic haemostatic assays in non-cardiac surgical settings: a systematic review and meta-analysis.

Authors:  Massimo Franchini; Carlo Mengoli; Mario Cruciani; Marco Marietta; Giuseppe Marano; Stefania Vaglio; Simonetta Pupella; Eva Veropalumbo; Francesca Masiello; Giancarlo M Liumbruno
Journal:  Blood Transfus       Date:  2018-02-26       Impact factor: 3.443

4.  Variations in clot phenotype following injury: The MA-R ratio and fragile clots.

Authors:  James Harrington; Ben L Zarzaur; Erin E Fox; Charles E Wade; John B Holcomb; Stephanie A Savage
Journal:  J Trauma Acute Care Surg       Date:  2022-03-01       Impact factor: 3.697

5.  Euglobulin clot lysis time reveals a high frequency of fibrinolytic activation in trauma.

Authors:  Anton Ilich; Vaibhav Kumar; Michael J Ferrara; Michael W Henderson; Denis F Noubouossie; Donald H Jenkins; Rosemary A Kozar; Myung S Park; Nigel S Key
Journal:  Thromb Res       Date:  2021-05-31       Impact factor: 10.407

Review 6.  Trauma-induced coagulopathy.

Authors:  Ernest E Moore; Hunter B Moore; Lucy Z Kornblith; Matthew D Neal; Maureane Hoffman; Nicola J Mutch; Herbert Schöchl; Beverley J Hunt; Angela Sauaia
Journal:  Nat Rev Dis Primers       Date:  2021-04-29       Impact factor: 65.038

7.  Coagulopathy as a Surrogate of Severity of Injury in Penetrating Brain Injury.

Authors:  Ali Mansour; Andrea Loggini; Fernando D Goldenberg; Christopher Kramer; Andrew M Naidech; Faten El Ammar; Valentina Vasenina; Brandyn Castro; Paramita Das; Peleg M Horowitz; Theodore Karrison; Tanya Zakrison; David Hampton; Selwyn O Rogers; Christos Lazaridis
Journal:  J Neurotrauma       Date:  2021-01-20       Impact factor: 4.869

8.  To Clot or Not: HELLP Syndrome and Disseminated Intravascular Coagulation in an Eclamptic Patient with Intrauterine Fetal Demise.

Authors:  Justin Walker; Anthony Bonavia
Journal:  Case Rep Anesthesiol       Date:  2020-07-07

9.  Modern Management of Bleeding, Clotting, and Coagulopathy in Trauma Patients: What Is the Role of Viscoelastic Assays?

Authors:  Sanjeev Dhara; Ernest E Moore; Michael B Yaffe; Hunter B Moore; Christopher D Barrett
Journal:  Curr Trauma Rep       Date:  2020-01-23

10.  Application of a plasmin generation assay to define pharmacodynamic effects of tranexamic acid in women undergoing cesarean delivery.

Authors:  Adam Miszta; Homa K Ahmadzia; Naomi L C Luban; Shuhui Li; Dong Guo; Lori A Holle; Jeffrey S Berger; Andra H James; Jogarao V S Gobburu; John van den Anker; Bas de Laat; Alisa S Wolberg
Journal:  J Thromb Haemost       Date:  2020-12-26       Impact factor: 5.824

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