| Literature DB >> 27894439 |
Abstract
Autoinflammatory disorders are disorders characterized by rash, arthritis, fever, and systemic inflammation. These disorders are caused by mutations in genes important in innate immune system sensors. This review highlights the workup of an individual with recurrent episodes of inflammation, features of these disorders, the genetic defects that cause these disorders, and the specific treatments available. Copyright ÂEntities:
Keywords: Autoinflammatory; Fever; IL-1beta; Innate immunity; TNF-α
Mesh:
Year: 2017 PMID: 27894439 DOI: 10.1016/j.pcl.2016.08.008
Source DB: PubMed Journal: Pediatr Clin North Am ISSN: 0031-3955 Impact factor: 3.278