Literature DB >> 27894058

A non-inferiority trial of Prolonged Exposure for posttraumatic stress disorder: In person versus home-based telehealth.

Ron Acierno1, Rebecca Knapp2, Peter Tuerk3, Amanda K Gilmore4, Carl Lejuez5, Kenneth Ruggiero6, Wendy Muzzy6, Leonard Egede7, Melba A Hernandez-Tejada6, Edna B Foa8.   

Abstract

This is the first randomized controlled trial to evaluate non-inferiority of Prolonged Exposure (PE) delivered via home-based telehealth (HBT) compared to standard in-person (IP) PE. One-hundred thirty two Veterans recruited from a Southeastern Veterans Affairs Medical Center and affiliated University who met criteria for posttraumatic stress disorder (PTSD) were randomized to receive PE via HBT or PE via IP. Results indicated that PE-HBT was non-inferior to PE-IP in terms of reducing PTSD scores at post-treatment, 3 and 6 month follow-up. However, non-inferiority hypotheses for depression were only supported at 6 month follow-up. HBT has great potential to reduce patient burden associated with receiving treatment in terms of travel time, travel cost, lost work, and stigma without sacrificing efficacy. These findings indicate that telehealth treatment delivered directly into patients' homes may dramatically increase the reach of this evidence-based therapy for PTSD without diminishing effectiveness. Published by Elsevier Ltd.

Entities:  

Keywords:  Non-inferiority; PTSD; Prolonged exposure; RCT; Telehealth

Mesh:

Year:  2016        PMID: 27894058      PMCID: PMC5222772          DOI: 10.1016/j.brat.2016.11.009

Source DB:  PubMed          Journal:  Behav Res Ther        ISSN: 0005-7967


  42 in total

1.  The President's New Freedom Commission: recommendations to transform mental health care in America.

Authors:  Michael F Hogan
Journal:  Psychiatr Serv       Date:  2003-11       Impact factor: 3.084

2.  Combat duty in Iraq and Afghanistan, mental health problems, and barriers to care.

Authors:  Charles W Hoge; Carl A Castro; Stephen C Messer; Dennis McGurk; Dave I Cotting; Robert L Koffman
Journal:  N Engl J Med       Date:  2004-07-01       Impact factor: 91.245

3.  Exposure therapy for PTSD delivered to veterans via telehealth: predictors of treatment completion and outcome and comparison to treatment delivered in person.

Authors:  Daniel F Gros; Matthew Yoder; Peter W Tuerk; Brian E Lozano; Ron Acierno
Journal:  Behav Ther       Date:  2011-01-27

4.  A randomized, controlled trial of child psychiatric assessments conducted using videoconferencing.

Authors:  R Elford; H White; R Bowering; A Ghandi; B Maddiggan; K St John; M House; J Harnett; R West; A Battcock
Journal:  J Telemed Telecare       Date:  2000       Impact factor: 6.184

5.  Group cognitive processing therapy delivered to veterans via telehealth: a pilot cohort.

Authors:  Leslie A Morland; Anna K Hynes; Margaret-Anne Mackintosh; Patricia A Resick; Kathleen M Chard
Journal:  J Trauma Stress       Date:  2011-07-25

6.  Health service utilization before and after evidence-based treatment for PTSD.

Authors:  Peter W Tuerk; Bethany Wangelin; Sheila A M Rauch; Clara E Dismuke; Matthew Yoder; Hugh Myrick; Afsoon Eftekhari; Ron Acierno
Journal:  Psychol Serv       Date:  2012-11-12

7.  BEHAVIORAL ACTIVATION AND THERAPEUTIC EXPOSURE FOR POSTTRAUMATIC STRESS DISORDER: A NONINFERIORITY TRIAL OF TREATMENT DELIVERED IN PERSON VERSUS HOME-BASED TELEHEALTH.

Authors:  Ron Acierno; Daniel F Gros; Kenneth J Ruggiero; B Melba A Hernandez-Tejada; Rebecca G Knapp; Carl W Lejuez; Wendy Muzzy; Christopher B Frueh; Leonard E Egede; Peter W Tuerk
Journal:  Depress Anxiety       Date:  2016-02-10       Impact factor: 6.505

8.  Bringing the war back home: mental health disorders among 103,788 US veterans returning from Iraq and Afghanistan seen at Department of Veterans Affairs facilities.

Authors:  Karen H Seal; Daniel Bertenthal; Christian R Miner; Saunak Sen; Charles Marmar
Journal:  Arch Intern Med       Date:  2007-03-12

9.  Telemedicine: a cost-reducing means of delivering psychotherapy to rural combat veterans with PTSD.

Authors:  Leslie A Morland; Michelle Raab; Margaret-Anne Mackintosh; Craig S Rosen; Clara E Dismuke; Carolyn J Greene; B Christopher Frueh
Journal:  Telemed J E Health       Date:  2013-08-09       Impact factor: 3.536

10.  Psychotherapy for depression in older veterans via telemedicine: a randomised, open-label, non-inferiority trial.

Authors:  Leonard E Egede; Ron Acierno; Rebecca G Knapp; Carl Lejuez; Melba Hernandez-Tejada; Elizabeth H Payne; B Christopher Frueh
Journal:  Lancet Psychiatry       Date:  2015-07-16       Impact factor: 27.083

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  39 in total

Review 1.  Use of Telepsychiatry in Emergency and Crisis Intervention: Current Evidence.

Authors:  Isabelle Reinhardt; Euphrosyne Gouzoulis-Mayfrank; Jürgen Zielasek
Journal:  Curr Psychiatry Rep       Date:  2019-07-01       Impact factor: 5.285

Review 2.  Telehealth and indigenous populations around the world: a systematic review on current modalities for physical and mental health.

Authors:  Aprill Z Dawson; Rebekah J Walker; Jennifer A Campbell; Tatiana M Davidson; Leonard E Egede
Journal:  Mhealth       Date:  2020-07-05

3.  An Examination of Social Support and PTSD Treatment Response During Prolonged Exposure.

Authors:  Matthew Price; Cynthia Luethcke Lancaster; Daniel F Gros; Alison C Legrand; Katherine van Stolk-Cooke; Ron Acierno
Journal:  Psychiatry       Date:  2018-07-18       Impact factor: 2.458

Review 4.  Recent Advances in Delivering Mental Health Treatment via Video to Home.

Authors:  Terri L Fletcher; Julianna B Hogan; Fallon Keegan; Michelle L Davis; Miryam Wassef; Stephanie Day; Jan A Lindsay
Journal:  Curr Psychiatry Rep       Date:  2018-07-21       Impact factor: 5.285

5.  Tailoring Cognitive Behavioral Therapy for Trauma-Exposed Persons Living With HIV.

Authors:  Cristina M López; Christine K Hahn; Amanda K Gilmore; Carla Kmett Danielson
Journal:  Cogn Behav Pract       Date:  2019-03-14

6.  Perceived risks and use of psychotherapy via telemedicine for patients at risk for suicide.

Authors:  Amanda K Gilmore; Erin F Ward-Ciesielski
Journal:  J Telemed Telecare       Date:  2017-10-08       Impact factor: 6.184

Review 7.  Clinical Lessons from Virtual House Calls in Mental Health: The Doctor Is in the House.

Authors:  Julianna Hogan; Derrecka Boykin; Christopher D Schneck; Anthony H Ecker; Terri L Fletcher; Jan A Lindsay; Jay H Shore
Journal:  Psychiatr Clin North Am       Date:  2019-10-01

8.  Emotion Dysregulation Predicts Dropout from Prolonged Exposure Treatment among Women Veterans with Military Sexual Trauma-Related Posttraumatic Stress Disorder.

Authors:  Amanda K Gilmore; Cristina Lopez; Wendy Muzzy; Wilson J Brown; Anouk Grubaugh; Daniel W Oesterle; Ron Acierno
Journal:  Womens Health Issues       Date:  2020-08-23

9.  Residual Sleep Problems Predict Reduced Response to Prolonged Exposure among Veterans with PTSD.

Authors:  Cristina M López; Cynthia Luethcke Lancaster; Daniel F Gros; Ron Acierno
Journal:  J Psychopathol Behav Assess       Date:  2017-07-24

10.  Re-engaging Dropouts of Prolonged Exposure for PTSD Delivered via Home-Based Telemedicine or In Person: Satisfaction with Veteran-to-Veteran Support.

Authors:  Melba A Hernandez-Tejada; Ron Acierno; David Sánchez-Carracedo
Journal:  J Behav Health Serv Res       Date:  2020-10-08       Impact factor: 1.505

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