Päivi Rahkola-Soisalo1, Daniel Altman2, Christian Falconer3, Edward Morcos3, Martin Rudnicki4, Tomi S Mikkola5. 1. University of Helsinki and Helsinki University Central Hospital, Department of Obstetrics and Gynecology, Finland. Electronic address: paivi.rahkola-soisalo@hus.fi. 2. Stockholm Urogynecological Clinic, Sweden; Division of Obstetrics and Gynecology, Karolinska Institutet Danderyd Hospital, Sweden. 3. Division of Obstetrics and Gynecology, Karolinska Institutet Danderyd Hospital, Sweden. 4. Odense University Hospital, Department of Obstetrics and Gynecology, Denmark. 5. University of Helsinki and Helsinki University Central Hospital, Department of Obstetrics and Gynecology, Finland; Folkhälsan Research Center, Helsinki, Finland.
Abstract
OBJECTIVE: To study the effects on quality of life in women operated for apical pelvic organ prolapse using the Vaginal Uphold™ System. STUDY DESIGN: In this prospective cohort study, women (n=207) with symptomatic apical prolapse, with or without cystocele, were operated using the Uphold™ Vaginal Support System. Follow-up for quality of life was performed at 12 months after surgery, and assessed by the PFDI-20, and PFIQ-7, and sexual function by the PISQ-12. We used odds ratios (ORs) with 95% confidence intervals (CIs) for outcome association analyses using logistic regression. RESULTS: At one-year follow-up majority of women experienced an overall postoperative improvement in quality of life (p<0.001). One year after surgery Uphold™ operation alone increased the risk for prolapse related bother as compared to Uphold™ combined with anterior colporraphy (POP-IQ-7; OR 2.1; 95% CI 1.01-4.3). The frequency of dyspareunia decreased postoperatively (p=0.004), however, after one-year, overall sexual function deteriorated significantly (p<0.001). The worsening in sexual function scores was mainly attributed to the partner related domain, whereas the behavioral-emotive and physical domains showed no significant changes. CONCLUSION: Apical prolapse repair using Uphold™ improved quality of life among our patients but worsened overall sexual function postoperatively.
OBJECTIVE: To study the effects on quality of life in women operated for apical pelvic organ prolapse using the Vaginal Uphold™ System. STUDY DESIGN: In this prospective cohort study, women (n=207) with symptomatic apical prolapse, with or without cystocele, were operated using the Uphold™ Vaginal Support System. Follow-up for quality of life was performed at 12 months after surgery, and assessed by the PFDI-20, and PFIQ-7, and sexual function by the PISQ-12. We used odds ratios (ORs) with 95% confidence intervals (CIs) for outcome association analyses using logistic regression. RESULTS: At one-year follow-up majority of women experienced an overall postoperative improvement in quality of life (p<0.001). One year after surgery Uphold™ operation alone increased the risk for prolapse related bother as compared to Uphold™ combined with anterior colporraphy (POP-IQ-7; OR 2.1; 95% CI 1.01-4.3). The frequency of dyspareunia decreased postoperatively (p=0.004), however, after one-year, overall sexual function deteriorated significantly (p<0.001). The worsening in sexual function scores was mainly attributed to the partner related domain, whereas the behavioral-emotive and physical domains showed no significant changes. CONCLUSION: Apical prolapse repair using Uphold™ improved quality of life among our patients but worsened overall sexual function postoperatively.