Literature DB >> 27893492

Safety of Local Intracutaneous Lidocaine Anesthesia Used by Dermatologic Surgeons for Skin Cancer Excision and Postcancer Reconstruction: Quantification of Standard Injection Volumes and Adverse Event Rates.

Murad Alam1, Matthew R Schaeffer, Amelia Geisler, Emily Poon, Scott W Fosko, Divya Srivastava.   

Abstract

BACKGROUND: Intracutaneous lidocaine is used for anesthesia in dermatologic surgery for skin cancer excision and repair with exceedingly low incidence of reported adverse events.
OBJECTIVE: To measure (1) the quantity of lidocaine typically used for facial skin cancer excision and reconstruction; and (2) the frequency and character of associated adverse events.
METHODS: Survey study of dermatologic surgeons with longitudinal reporting. Reported practice during 10 business days: (1) mean volume of 1% lidocaine per skin cancer excision; (2) maximum per excision; (3) mean per reconstruction; and (4) maximum per reconstruction.
RESULTS: A total of 437 of 1,175 subjects contacted (37.2%) responded. Mean per excision was 3.44 mL (SD: 2.97), and reconstruction 11.70 mL (10.14). Maximum per excision was 6.54 mL (4.23), and reconstruction was 15.85 mL (10.39). No cases of lidocaine toxicity were reported, diagnosed, or treated. Incidence of adverse events possibly anesthesia related was >0.15%, with most (0.13%) being mild cases of dizziness, drowsiness, or lightheadedness from epinephrine tachycardia.
CONCLUSION: Toxicity associated with local anesthesia other than lidocaine was not studied. Volumes of lidocaine in skin cancer excision and repair are modest and within safe limits. Lidocaine toxicity is exceedingly rare to entirely absent. For comparable indications, lidocaine is safer than conscious sedation or general anesthesia.

Entities:  

Mesh:

Substances:

Year:  2016        PMID: 27893492     DOI: 10.1097/DSS.0000000000000907

Source DB:  PubMed          Journal:  Dermatol Surg        ISSN: 1076-0512            Impact factor:   3.398


  3 in total

1.  Efficacy of Local Anesthesia in the Face and Scalp: A Prospective Trial.

Authors:  Tyler Safran; Dino Zammit; Jonathan Kanevsky; Manish Khanna
Journal:  Plast Reconstr Surg Glob Open       Date:  2019-05-16

2.  Ketorolac plus Lidocaine vs Lidocaine for pain relief following core needle soft tissue biopsy: A CONSORT-compliant double-blind randomized controlled study.

Authors:  Thanapon Chobpenthai; Thammasin Ingviya; Pichaya Thanindratarn; Rattakorn Jaiwithee; Kulwadee Sutthivaiyakit
Journal:  Medicine (Baltimore)       Date:  2021-02-19       Impact factor: 1.817

Review 3.  Safety of local anesthetics.

Authors:  Ana Carolina Figueiredo Pereira Cherobin; Glaysson Tassara Tavares
Journal:  An Bras Dermatol       Date:  2019-12-18       Impact factor: 1.896

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.