| Literature DB >> 27892867 |
Jiang Yu1, Yuyu Zhang1, Yijun Du1, Jun Li1, Baohua Huang1, Wenbo Sun1, Xiaoyan Cong1, Jun Peng2, Sufang Ren1, Lihui Gou1, Jianli Shi1, Zhi Chen1, Lei Chen1, Jianda Li1, Jie Yang1, Jiaqiang Wu3, Jinbao Wang4.
Abstract
The use of BALB/c mouse as an alternative model to study Haemophilus parasuis (HPS) infections was evaluated, supplying the serotyping scheme by comparing the pathogenicity of different serovar HPS in pigs and mice challenge using statistical analysis. Results showed that the pathogenicity of different serovar HPS in mouse was consistent with in pigs, proving that this model is a viable alternative to pigs. It provides a convenient methodology for determining the virulence of HPS strains.Entities:
Keywords: BALB/c mouse; Haemophilus parasuis; Model
Mesh：
Year: 2016 PMID： 27892867 DOI： 10.1016/j.rvsc.2016.10.011
Source DB: PubMed Journal: Res Vet Sci ISSN： 0034-5288 Impact factor: 2.534