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Literature DB >> 27892768

TFEB and TFE3: The art of multi-tasking under stress conditions.

Abstract

Cellular adaptation response to a myriad of stressors is key for survival. The lysosomal/autophagy pathway is inextricably connected to the stress response regulation. Two transcription factors, TFEB and TFE3, have recently emerged as master regulators of this degradative pathway. Their function modulating different cellular pathways will be discussed.

Entities: Gene

Keywords: TFE3; TFEB; autophagy; lysosomes; stress

Mesh：

Substances：

Year: 2016 PMID： 27892768 PMCID： PMC5279710 DOI： 10.1080/21541264.2016.1264353

Source DB: PubMed Journal: Transcription ISSN： 2154-1272

49 in total

1. Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.

Authors: Nao Hosokawa; Taichi Hara; Takeshi Kaizuka; Chieko Kishi; Akito Takamura; Yutaka Miura; Shun-ichiro Iemura; Tohru Natsume; Kenji Takehana; Naoyuki Yamada; Jun-Lin Guan; Noriko Oshiro; Noboru Mizushima
Journal: Mol Biol Cell Date: 2009-02-11 Impact factor: 4.138

2. A RANKL-PKCβ-TFEB signaling cascade is necessary for lysosomal biogenesis in osteoclasts.

Authors: Mathieu Ferron; Carmine Settembre; Junko Shimazu; Julie Lacombe; Shigeaki Kato; David J Rawlings; Andrea Ballabio; Gerard Karsenty
Journal: Genes Dev Date: 2013-04-18 Impact factor: 11.361

3. The absence of the transcription activator TFE3 impairs activation of B cells in vivo.

Authors: K Merrell; S Wells; A Henderson; J Gorman; F Alt; A Stall; K Calame
Journal: Mol Cell Biol Date: 1997-06 Impact factor: 4.272

4. Transcription Factor Tfe3 Directly Regulates Pgc-1alpha in Muscle.

Authors: Nunciada Salma; Jun S Song; Zoltan Arany; David E Fisher
Journal: J Cell Physiol Date: 2015-10 Impact factor: 6.384

5. PGC-1α rescues Huntington's disease proteotoxicity by preventing oxidative stress and promoting TFEB function.

Authors: Taiji Tsunemi; Travis D Ashe; Bradley E Morrison; Kathryn R Soriano; Jonathan Au; Ruben A Vázquez Roque; Eduardo R Lazarowski; Vincent A Damian; Eliezer Masliah; Albert R La Spada
Journal: Sci Transl Med Date: 2012-07-11 Impact factor: 17.956

6. The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis.

Authors: Agnes Roczniak-Ferguson; Constance S Petit; Florian Froehlich; Sharon Qian; Jennifer Ky; Brittany Angarola; Tobias C Walther; Shawn M Ferguson
Journal: Sci Signal Date: 2012-06-12 Impact factor: 8.192

7. MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability.

Authors: Eyleen J O'Rourke; Gary Ruvkun
Journal: Nat Cell Biol Date: 2013-04-21 Impact factor: 28.824

8. A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB.

Authors: Carmine Settembre; Roberto Zoncu; Diego L Medina; Francesco Vetrini; Serkan Erdin; SerpilUckac Erdin; Tuong Huynh; Mathieu Ferron; Gerard Karsenty; Michel C Vellard; Valeria Facchinetti; David M Sabatini; Andrea Ballabio
Journal: EMBO J Date: 2012-02-17 Impact factor: 11.598

9. MiT/TFE transcription factors are activated during mitophagy downstream of Parkin and Atg5.

Authors: Catherine L Nezich; Chunxin Wang; Adam I Fogel; Richard J Youle
Journal: J Cell Biol Date: 2015-08-03 Impact factor: 10.539

10. Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy.

Authors: Davor Ivankovic; Kai-Yin Chau; Anthony H V Schapira; Matthew E Gegg
Journal: J Neurochem Date: 2015-11-24 Impact factor: 5.372

14 in total

1. Lysosomal Dysfunction in Down Syndrome Is APP-Dependent and Mediated by APP-βCTF (C99).

Authors: Ying Jiang; Yutaka Sato; Eunju Im; Martin Berg; Matteo Bordi; Sandipkumar Darji; Asok Kumar; Panaiyur S Mohan; Urmi Bandyopadhyay; Antonio Diaz; Ana Maria Cuervo; Ralph A Nixon
Journal: J Neurosci Date: 2019-05-01 Impact factor: 6.167

2. AKT inhibition-mediated dephosphorylation of TFE3 promotes overactive autophagy independent of MTORC1 in cadmium-exposed bone mesenchymal stem cells.

Authors: Huifeng Pi; Min Li; Lingyun Zou; Min Yang; Ping Deng; Tengfei Fan; Menyu Liu; Li Tian; Manyu Tu; Jia Xie; Mengyan Chen; Huijuan Li; Yu Xi; Lei Zhang; Mindi He; Yonghui Lu; Chunhai Chen; Tao Zhang; Zheng Wang; Zhengping Yu; Feng Gao; Zhou Zhou
Journal: Autophagy Date: 2018-10-20 Impact factor: 16.016

3. Loss of Hepatic Transcription Factor EB Attenuates Alcohol-Associated Liver Carcinogenesis.

Authors: Xiaojuan Chao; Shaogui Wang; Madeline Hlobik; Andrea Ballabio; Hong-Min Ni; Wen-Xing Ding
Journal: Am J Pathol Date: 2021-10-27 Impact factor: 4.307

Review 4. Autophagy in cancer cell remodeling and quality control.

Authors: Grace A Hernandez; Rushika M Perera
Journal: Mol Cell Date: 2022-04-21 Impact factor: 19.328

5. Uromodulin p.Cys147Trp mutation drives kidney disease by activating ER stress and apoptosis.

Authors: Bryce G Johnson; Lan T Dang; Graham Marsh; Allie M Roach; Zebulon G Levine; Anthony Monti; Deepak Reyon; Lionel Feigenbaum; Jeremy S Duffield
Journal: J Clin Invest Date: 2017-10-09 Impact factor: 14.808

6. HSP90 inhibitors induce GPNMB cell-surface expression by modulating lysosomal positioning and sensitize breast cancer cells to glembatumumab vedotin.

Authors: Marco Biondini; Alex Kiepas; Leeanna El-Houjeiri; Matthew G Annis; Brian E Hsu; Anne-Marie Fortier; Geneviève Morin; José A Martina; Isabelle Sirois; Adriana Aguilar-Mahecha; Tina Gruosso; Shawn McGuirk; April A N Rose; Unal M Tokat; Radia M Johnson; Ozgur Sahin; Eric Bareke; Julie St-Pierre; Morag Park; Mark Basik; Jacek Majewski; Rosa Puertollano; Arnim Pause; Sidong Huang; Tibor Keler; Peter M Siegel
Journal: Oncogene Date: 2022-02-02 Impact factor: 8.756