Literature DB >> 27891571

High-Risk Medications in Hospitalized Elderly Adults: Are We Making It Easy to Do the Wrong Thing?

Nina L Blachman1, Rosanne M Leipzig2,3, Madhu Mazumdar4, Jashvant Poeran4.   

Abstract

OBJECTIVES: To examine dosages of high-risk medications administered to elderly adults who fall in the hospital and to determine whether electronic default doses are appropriate for elderly adults.
DESIGN: Retrospective.
SETTING: Large urban academic hospital. PARTICIPANTS: Individuals aged 65 and older experiencing a fall. MEASUREMENTS: Prescribed daily dosages and use of high-risk medications (opiates, benzodiazepines, benzodiazepine-receptor agonists (BRAs), sleep medications, muscle relaxants, antipsychotics) administered within 24 hours before a fall were ascertained and compared with published recommended dosages for older adults and the hospital's electronic medical record (EMR) default doses for these drugs.
RESULTS: Of 328 falls, 62% occurred in individuals administered at least one high-risk medication within the 24 hours before the fall, with 16% of the falls involving individuals receiving two, and another 16% in individuals receiving three or more. High-risk medications were often administered at higher-than-recommended geriatric daily doses, in particular benzodiazepines and BRAs, for which the dose was higher than recommended in 29 of 51 cases (57%). Hospital EMR default doses were higher than recommended for 41% (12/29) of medications examined.
CONCLUSION: High-risk medications were administered to older fallers. Doses administered and EMR default doses were often higher than recommended. Decreasing EMR default doses for individuals aged 65 and older and warnings about the cumulative numbers of high-risk medications prescribed per person may be simple interventions that could decrease inpatient falls.
© 2016, Copyright the Authors Journal compilation © 2016, The American Geriatrics Society.

Entities:  

Keywords:  default dosing; falls; high-risk medications

Mesh:

Substances:

Year:  2016        PMID: 27891571     DOI: 10.1111/jgs.14703

Source DB:  PubMed          Journal:  J Am Geriatr Soc        ISSN: 0002-8614            Impact factor:   5.562


  5 in total

1.  Characteristics of New-Onset and Chronic Sleep Medication Users Among Older Adults: A Retrospective Study of a US Medigap Plan Population using Propensity Score Matching.

Authors:  Shirley Musich; Shaohung S Wang; Luke B Slindee; Lynn Saphire; Ellen Wicker
Journal:  Drugs Aging       Date:  2018-05       Impact factor: 3.923

2.  Increasing Rates of Opioid Misuse Among Older Adults Visiting Emergency Departments.

Authors:  Mary W Carter; Bo Kyum Yang; Marsha Davenport; Allison Kabel
Journal:  Innov Aging       Date:  2019-03-07

3.  CYP2D6-inhibiting drugs and risk of fall injuries after newly initiated antidepressant and antipsychotic therapy in a Swedish, register-based case-crossover study.

Authors:  Marja-Liisa Dahl; Karin Leander; Max Vikström; Clara Frumerie; Sofia Nordenmalm; Jette Möller; Karin Söderberg-Löfdal
Journal:  Sci Rep       Date:  2021-03-11       Impact factor: 4.379

4.  Machine learning for predicting readmission risk among the frail: Explainable AI for healthcare.

Authors:  Somya D Mohanty; Deborah Lekan; Thomas P McCoy; Marjorie Jenkins; Prashanti Manda
Journal:  Patterns (N Y)       Date:  2021-12-03

5.  Balancing Safety, Comfort, and Fall Risk: An Intervention to Limit Opioid and Benzodiazepine Prescriptions for Geriatric Patients.

Authors:  Ainsley Bloomer; Meghan Wally; Gisele Bailey; Tamar Roomian; Madhav Karunakar; Joseph R Hsu; Rachel Seymour; Michael Beuhler; Michael Bosse; Michael Gibbs; Christopher Griggs; Steven Jarrett; Daniel Leas; Susan Odum; Michael Runyon; Animita Saha; Ziquing Yu; Brad Watling; Stephen Wyatt
Journal:  Geriatr Orthop Surg Rehabil       Date:  2022-10-12
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.