Literature DB >> 27891455

Unmasking the Effect of Analgesics on Endodontic Diagnosis Using a Novel Bite Force Sensor Device: A Prospective, Randomized Clinical Trial.

Sushil Kishnani1, Suparna Ganguly Saha2, Anuj Bhardwaj3, Sandeep Dubey4, Mainak Saha5, Shubham Kala4, Sohini Jain6, Shweta Narwani7.   

Abstract

INTRODUCTION: A definitive diagnosis is of primary importance before initiating any endodontic treatment; yet, there are occasions when the dental professional is unable to accurately reproduce the patient's chief complaint, as it can pose a dilemma and may require consideration of multiple variables in order to reach an accurate diagnosis. So to overcome this problem, a methodical approach in providing endodontic treatment should be implemented which includes diagnosis, definitive dental treatment and adjunctive drug therapy, known as the "3D" strategy. AIM: The purpose of this study was to evaluate the possible "masking" effect of these analgesics on endodontic diagnosis using a novel bite force sensor device.
MATERIALS AND METHODS: A total of 90 patients with endodontic pain were selected and they were given either a placebo or 400 mg ibuprofen (brufen) or 50mg diclofenac sodium (voveron). Both patients and operators were completely blinded to the drugs administered. Bite force tolerance values were noted before and one hour after administration of medication using the self designed bite force sensor.
RESULTS: The pre- and post-bite force tolerance values were tabulated for both contralateral and affected tooth. For the affected tooth, there was statistically significant difference between pre- and post-bite force tolerance values in Group I (i.e., ibuprofen) and Group II (i.e., diclofenac sodium) (p<0.05) with no significant difference observed in Group III (placebo).
CONCLUSION: The easily available over the counter self administered analgesics in addition to providing symptomatic relief to patients suffering from symptomatic apical periodontitis may also cloud the definitive diagnosis of the clinician, thus jeopardising the treatment plan. The self designed bite force sensor was effective in arriving at a definitive diagnosis in teeth with chronic irreversible pulpitis with symptomatic apical periodontitis, where the allodynia has been camouflaged by the use of analgesics like ibuprofen and diclofenac sodium.

Entities:  

Keywords:  Diclofenac sodium; Ibuprofen; Pain; Placebo

Year:  2016        PMID: 27891455      PMCID: PMC5121801          DOI: 10.7860/JCDR/2016/21116.8640

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  10 in total

Review 1.  New advances in the management of endodontic pain emergencies.

Authors:  Kenneth M Hargreaves; Karl Keiser
Journal:  J Calif Dent Assoc       Date:  2004-06

2.  The assessment of pulpal vitality.

Authors:  A H Rowe; T R Pitt Ford
Journal:  Int Endod J       Date:  1990-03       Impact factor: 5.264

Review 3.  Diclofenac: an update on its mechanism of action and safety profile.

Authors:  Tong J Gan
Journal:  Curr Med Res Opin       Date:  2010-07       Impact factor: 2.580

4.  Effect of Ibuprofen on masking endodontic diagnosis.

Authors:  Jason K Read; Scott B McClanahan; Asma A Khan; Scott Lunos; Walter R Bowles
Journal:  J Endod       Date:  2014-06-25       Impact factor: 4.171

5.  Coping with tooth pain: a qualitative study of lay management strategies and professional consultation.

Authors:  E P Stoller; G H Gilbert; M A Pyle; R P Duncan
Journal:  Spec Care Dentist       Date:  2001 Nov-Dec

6.  An analysis of current analgesic preferences for endodontic pain management.

Authors:  André K Mickel; Andrew P Wright; Sami Chogle; Jefferson J Jones; Igor Kantorovich; Francis Curd
Journal:  J Endod       Date:  2006-10-19       Impact factor: 4.171

7.  The incidence of mechanical allodynia in patients with irreversible pulpitis.

Authors:  Christopher B Owatz; Asma A Khan; William G Schindler; Scott A Schwartz; Karl Keiser; Kenneth M Hargreaves
Journal:  J Endod       Date:  2007-03-06       Impact factor: 4.171

8.  Comparison of preoperative pain and medication use in emergency patients presenting with irreversible pulpitis or teeth with necrotic pulps.

Authors:  John M Nusstein; Mike Beck
Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod       Date:  2003-08

9.  Measurement of mechanical allodynia and local anesthetic efficacy in patients with irreversible pulpitis and acute periradicular periodontitis.

Authors:  Asma A Khan; Christopher B Owatz; William G Schindler; Scott A Schwartz; Karl Keiser; Kenneth M Hargreaves
Journal:  J Endod       Date:  2007-03-26       Impact factor: 4.171

10.  Selective COX-2 Inhibitors: A Review of Their Structure-Activity Relationships.

Authors:  Afshin Zarghi; Sara Arfaei
Journal:  Iran J Pharm Res       Date:  2011       Impact factor: 1.696

  10 in total

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