Literature DB >> 27891377

Immune Thrombocytopenia as a Presenting Manifestation of Tuberculosis- Challenge in Resource Constraint Settings.

Deba Prasad Dhibar1, Kamal Kant Sahu2, Varun Dhir3, Surjit Singh4.   

Abstract

Tuberculosis can infect almost any organ of our body leading to various presentations and its complication. Various haematological manifestations of tuberculosis are well known. But isolated thrombocytopenia and Immune Thrombocytopenia (ITP) in patients with tuberculosis is very rare. Here we report a case of young man who presented with acute onset of bleeding manifestations in the form of epistaxis and macroscopic haematuria with platelets count of 5×109/L. The patient was diagnosed to have ITP along with clinical and radiological evidence of active tuberculosis. The patient was treated with Anti Tubercular Therapy (ATT) along with Intravenous (IV) pulse of methyl prednisolone followed by tapering dose of oral prednisolone.

Entities:  

Keywords:  Anti tubercular therapy; Bleeding manifestations; Prednisolone

Year:  2016        PMID: 27891377      PMCID: PMC5121715          DOI: 10.7860/JCDR/2016/20911.8612

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  10 in total

1.  Diagnosis and treatment of idiopathic thrombocytopenic purpura: recommendations of the American Society of Hematology. The American Society of Hematology ITP Practice Guideline Panel.

Authors: 
Journal:  Ann Intern Med       Date:  1997-02-15       Impact factor: 25.391

Review 2.  The American Society of Hematology 2011 evidence-based practice guideline for immune thrombocytopenia.

Authors:  Cindy Neunert; Wendy Lim; Mark Crowther; Alan Cohen; Lawrence Solberg; Mark A Crowther
Journal:  Blood       Date:  2011-02-16       Impact factor: 22.113

3.  Active pulmonary tuberculosis manifesting with idiopathic thrombocytopenic purpura: a rare presentation.

Authors:  Payam Tabarsi; Muayad Aghali Merza; Majid Marjani
Journal:  Braz J Infect Dis       Date:  2010 Nov-Dec       Impact factor: 1.949

4.  Miliary tuberculosis: clinical manifestations, diagnosis and outcome in 38 adults.

Authors:  A Mert; M Bilir; F Tabak; R Ozaras; R Ozturk; H Senturk; H Aki; N Seyhan; T Karayel; Y Aktuglu
Journal:  Respirology       Date:  2001-09       Impact factor: 6.424

5.  Haematological abnormalities in children with tuberculosis.

Authors:  G Wessels; H S Schaaf; N Beyers; R P Gie; E Nel; P R Donald
Journal:  J Trop Pediatr       Date:  1999-10       Impact factor: 1.165

Review 6.  Immune thrombocytopenia: a rare presenting manifestation of tuberculosis.

Authors:  M W Ghobrial; M A Albornoz
Journal:  Am J Hematol       Date:  2001-06       Impact factor: 10.047

7.  Tuberculosis presenting as immune thrombocytopenic purpura.

Authors:  S A al-Majed; A K al-Momen; F A al-Kassimi; A al-Zeer; A M Kambal; H Baaqil
Journal:  Acta Haematol       Date:  1995       Impact factor: 2.195

8.  Immune thrombocytopenia in tuberculosis: causal or coincidental?

Authors:  Gopalakrishnan Srividya; Gopalakrishna Pillai Syamala Nikhila; Adusumilli Venkatakrishna Kaushik; Kuppusamy Jayachandran
Journal:  J Glob Infect Dis       Date:  2014-07

9.  Tuberculosis presenting as immune thrombocytopenic purpura.

Authors:  Fahir Ozkalemkas; Ridvan Ali; Atilla Ozkan; Tulay Ozcelik; Vildan Ozkocaman; Esra Kunt-Uzaslan; Beril Bahadir-Erdogan; Halis Akalin
Journal:  Ann Clin Microbiol Antimicrob       Date:  2004-09-06       Impact factor: 3.944

10.  Immune thrombocytopenic purpura in a case of tubercular pleural effusion: A rare presentation.

Authors:  Souren Pal; Nirendra Mohan Biswas; Saikat Dutta; Ramkrishna Brahmachari
Journal:  Lung India       Date:  2016 Jan-Feb
  10 in total
  5 in total

1.  Rifampin Induced Thrombotic Thrombocytopenic Purpura.

Authors:  Hannah Hamad; Kamal Kant Sahu; Steven Dunn; Lucia Milla; Alice Caffery; Nahida Islam
Journal:  Indian J Hematol Blood Transfus       Date:  2020-01-10       Impact factor: 0.900

2.  Aerococcus-Related Infections and their Significance: A 9-Year Retrospective Study.

Authors:  Kamal Kant Sahu; Amos Lal; Ajay Kumar Mishra; George M Abraham
Journal:  J Microsc Ultrastruct       Date:  2020-11-09

3.  Real-world Experience of Rituximab in Immune Thrombocytopenia.

Authors:  Kundan Mishra; Suman Kumar; Aditya Jandial; Kamal Kant Sahu; Rajeev Sandal; Ankur Ahuja; Sanjeev Khera; Yanamandra Uday; Rajiv Kumar; Rajan Kapoor; Tarun Verma; Sanjeevan Sharma; Jasjit Singh; Satyaranjan Das; Tathagat Chatterjee; Ajay Sharma; Velu Nair
Journal:  Indian J Hematol Blood Transfus       Date:  2021-01-01       Impact factor: 0.915

4.  Challenges for management of immune thrombocytopenia during COVID-19 pandemic.

Authors:  Kamal Kant Sahu; Ahmad Daniyal Siddiqui; Nima Rezaei; Jan Cerny
Journal:  J Med Virol       Date:  2020-07-11       Impact factor: 20.693

5.  Impact of COVID-19 Pandemic on Patients with Immune Thrombocytopaenia.

Authors:  María-Teresa Álvarez Román; Víctor Jiménez Yuste; Sara García Barcenilla; Andrés Ramírez López; Elena Monzón Manzano; Beatriz de la Cruz Benito; Paula Acuña Butta; María Isabel Rivas Pollmar; Roberto Trelles Martínez; Elena González Zorrilla; Mónica Martín Salces; Tamara Cebanu; Nora V Butta
Journal:  Medicina (Kaunas)       Date:  2021-03-01       Impact factor: 2.430

  5 in total

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