Literature DB >> 27891332

Is dilution important: Factitious Total Creatine Kinase in case of Rhabdomyolysis?

Sunil Kumar Nanda1, Asha Dinakaran2, Lopamudra Ray3.   

Abstract

Factitious test reports may result in incorrect diagnosis and incorrect management. Such incorrect diagnosis can be prevented by a vigilant biochemist. We report a case of Rhabdomyolysis presenting with extremely low total Creatine Kinase (CK) levels which was factitious. Running the sample in dilution resulted in a very high value of total CK which could have been missed if the sample was not run in dilution and the diagnosis of Rhabdomyolysis could have been missed.

Entities:  

Keywords:  Incorrect diagnosis; Muscle injury; Sample dilution; Substrate depletion

Year:  2016        PMID： 27891332      PMCID： PMC5121670          DOI： 10.7860/JCDR/2016/22338.8738

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN： 0973-709X


  10 in total

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Review 5.  Biochemical markers of muscular damage.

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Review 6.  The detection and prevention of errors in laboratory medicine.

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Journal:  Ann Clin Biochem       Date:  2009-12-01       Impact factor: 2.057

7.  Utility of Serum Creatinine, Creatine Kinase and Urinary Myoglobin in Detecting Acute Renal Failure due to Rhabdomyolysis in Trauma and Electrical Burns Patients.

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Review 8.  Rhabdomyolysis. Pathophysiology, recognition, and management.

Authors:  Laura M Criddle
Journal:  Crit Care Nurse       Date:  2003-12       Impact factor: 1.708

9.  Over a millon Creatine Kinase due to a heavy work-out: A case report.

Authors:  Pablo Casares; Jorge Marull
Journal:  Cases J       Date:  2008-09-20

10.  Rhabdomyolysis due to the additive effect of statin therapy and hypothyroidism: a case report.

Authors:  Ekrem Yeter; Telat Keles; Tahir Durmaz; Engin Bozkurt
Journal:  J Med Case Rep       Date:  2007-11-10
  10 in total
  2 in total

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Journal:  World J Clin Cases       Date:  2019-12-26       Impact factor: 1.337

Review 2.  Rhabdomyolysis: Revisited.

Authors:  Ankur Gupta; Peter Thorson; Krishnam R Penmatsa; Pritam Gupta
Journal:  Ulster Med J       Date:  2021-07-08
  2 in total

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