Literature DB >> 27891327

Analysis of Fetal Palate to Assist Pre-natal Ultrasound.

Anjali Shastry1, Yogitha Ravindranath2, Roopa Ravindranath3.   

Abstract

INTRODUCTION: Cleft palate is one of the major facial congenital malformation in newborns. Pre-natal detection of this malformation is limited to detection of clefting of hard palate but isolated soft palate clefting still remains challenge for sonologists. As Indian literature is limited present study was attempted to provide dimensions and position of fetal palate by digitized images. AIM: To study dimensions, position and differences in parameters between second and third trimester fetuses.
MATERIALS AND METHODS: Median sagittal section of 32 formalin fixed fetuses was selected from the Department of Anatomy, St John's Medical College, Bangalore, Karnataka, India. Anatomical landmarks-The Nasion (N), Sellaturcica (S), Anterior Nasal Spine (ANS), Posterior Nasal Spine (PNS), tip of Uvula (U) were marked on sections. Length of hard palate (from ANS to PNS), Length of soft palate (from PNS to U), Hard palate/soft palate angle was defined. The anterior position of soft palate and its posterior position in relation to anterior cranial base were marked as N-S-PNS and N-S-U angle, respectively. The measurements were acquired directly from the digitized images using ImageJ software. Statistical analysis was done using SPSS 16.
RESULTS: The mean values of ANS-PNS and PNS-U were 23.59±3.69mm and 14.39±2.70mm, respectively. The mean values of hard palate/soft palate angle, N-S-PNS and N-S-U angle were 144.720±11.11,51.150±9.09 and 93.370±9.58, respectively. Significant difference was noted between trimesters for length of hard and soft palate but not for palatal angles.
CONCLUSION: During Pre-natal assessment of cleft palate, it is important for sonologist to keep in mind that the dimensions of palate proportionately increased in last two trimesters while the position remains constant.

Entities:  

Keywords:  Cleft palate; Facial growth; Fetal development; Pre-natal diagnosis; Soft palate; Ultrasonography

Year:  2016        PMID: 27891327      PMCID: PMC5121665          DOI: 10.7860/JCDR/2016/21170.8709

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  8 in total

1.  Prenatal ultrasound examination of the secondary palate.

Authors:  S Campbell
Journal:  Ultrasound Obstet Gynecol       Date:  2007-02       Impact factor: 7.299

2.  Sonographic assessment of normal fetal palate using three-dimensional imaging: a new technique.

Authors:  J M Faure; G Captier; M Bäumler; P Boulot
Journal:  Ultrasound Obstet Gynecol       Date:  2007-02       Impact factor: 7.299

3.  Prenatal diagnosis of an isolated incomplete V-shaped cleft palate using a new three-dimensional ultrasound technique investigation.

Authors:  Jean-Michel Faure; Marcel Bäumler; Michèle Bigorre; Guillaume Captier; Pierre Boulot
Journal:  Surg Radiol Anat       Date:  2007-11-13       Impact factor: 1.246

4.  Anatomy and growth of the fetal soft palate: a cadaveric study to improve its ultrasonographic observation.

Authors:  Guillaume Captier; Jean-Michel Faure; Marcel Baümler; François Bonnel; Jean-Pierre Daures
Journal:  Cleft Palate Craniofac J       Date:  2008-02-20

5.  The accuracy of antenatal ultrasound in the detection of facial clefts in a low-risk screening population.

Authors:  C Cash; P Set; N Coleman
Journal:  Ultrasound Obstet Gynecol       Date:  2001-11       Impact factor: 7.299

6.  Prenatal detection of facial clefts.

Authors:  K Sohan; M Freer; N Mercer; P Soothill; P Kyle
Journal:  Fetal Diagn Ther       Date:  2001 Jul-Aug       Impact factor: 2.587

7.  Evaluation of prenatal diagnosis of cleft lip with or without cleft palate and cleft palate by ultrasound: experience from 20 European registries. EUROSCAN study group.

Authors:  M Clementi; R Tenconi; F Bianchi; C Stoll
Journal:  Prenat Diagn       Date:  2000-11       Impact factor: 3.050

8.  Associated anomalies in multi-malformed infants with cleft lip and palate: An epidemiologic study of nearly 6 million births in 23 EUROCAT registries.

Authors:  Elisa Calzolari; Anna Pierini; Gianni Astolfi; Fabrizio Bianchi; Amanda J Neville; Francesca Rivieri
Journal:  Am J Med Genet A       Date:  2007-03-15       Impact factor: 2.802

  8 in total

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