Lavanya Parthasarathy1, Vaman Khadilkar, Shashi Chiplonkar, Anuradha Khadilkar. 1. Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharashtra, India. Correspondence to: Dr Anuradha Khadilkar, Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, 32 Sassoon Road, Pune.411 001, India. anuradhavkhadilkar@gmail.com.
Abstract
OBJECTIVE: To study longitudinal growth in children with type 1 diabetes mellitus. METHODS: Anthropometry, disease duration, insulin regimens and HbA1C recorded from patients with diabetes enrolled in a specialty clinic. RESULTS: 160 children (75 boys; mean (SD) age 9.4 (3.3) y) were enrolled. 35% children had low (<25th centile) height velocity. Disease duration and HbA1C affected height velocity (adjusted for puberty). Children on basal-bolus had higher height velocity Z scores than those on a split mix regimen [(0.5(1.6) vs. -0.3(1.4), P<0.05)]. Children diagnosed before 5 years of age had lowest height velocity. Of the children who reached final height, 53% remained below target height. CONCLUSION: Children with type 1 diabetes mellitus have lower height velocity compared to healthy children; those diagnosed at younger age were at higher risk for growth failure.
OBJECTIVE: To study longitudinal growth in children with type 1 diabetes mellitus. METHODS: Anthropometry, disease duration, insulin regimens and HbA1C recorded from patients with diabetes enrolled in a specialty clinic. RESULTS: 160 children (75 boys; mean (SD) age 9.4 (3.3) y) were enrolled. 35% children had low (<25th centile) height velocity. Disease duration and HbA1C affected height velocity (adjusted for puberty). Children on basal-bolus had higher height velocity Z scores than those on a split mix regimen [(0.5(1.6) vs. -0.3(1.4), P<0.05)]. Children diagnosed before 5 years of age had lowest height velocity. Of the children who reached final height, 53% remained below target height. CONCLUSION:Children with type 1 diabetes mellitus have lower height velocity compared to healthy children; those diagnosed at younger age were at higher risk for growth failure.
Authors: Belinda S Lennerz; Anna Barton; Richard K Bernstein; R David Dikeman; Carrie Diulus; Sarah Hallberg; Erinn T Rhodes; Cara B Ebbeling; Eric C Westman; William S Yancy; David S Ludwig Journal: Pediatrics Date: 2018-05-07 Impact factor: 7.124
Authors: Elisa Santi; Giorgia Tascini; Giada Toni; Maria Giulia Berioli; Susanna Esposito Journal: Int J Environ Res Public Health Date: 2019-09-30 Impact factor: 3.390