Literature DB >> 27888238

Rational design of a parthenolide-based drug regimen that selectively eradicates acute myelogenous leukemia stem cells.

Shanshan Pei, Mohammad Minhajuddin, Angelo D'Alessandro, Travis Nemkov, Brett M Stevens, Biniam Adane, Nabilah Khan, Fred K Hagen, Vinod K Yadav, Subhajyoti De, John M Ashton, Kirk C Hansen, Jonathan A Gutman, Daniel A Pollyea, Peter A Crooks, Clayton Smith, Craig T Jordan.   

Abstract

Entities:  

Year:  2016        PMID： 27888238      PMCID： PMC5122795          DOI： 10.1074/jbc.A116.750653

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


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  5 in total

1.  Anticancer activity profiling of parthenolide analogs generated via P450-mediated chemoenzymatic synthesis.

Authors:  Hanan Alwaseem; Benjamin J Frisch; Rudi Fasan
Journal:  Bioorg Med Chem       Date:  2017-08-08       Impact factor: 3.641

Review 2.  Redox Paradox: A Novel Approach to Therapeutics-Resistant Cancer.

Authors:  Luksana Chaiswing; William H St Clair; Daret K St Clair
Journal:  Antioxid Redox Signal       Date:  2018-02-21       Impact factor: 8.401

3.  Symbiotic prodrugs (SymProDs) dual targeting of NFkappaB and CDK.

Authors:  Sandeep Rana; Smit Kour; Yogesh A Sonawane; Caroline M Robb; Jacob I Contreras; Smitha Kizhake; Muhammad Zahid; Adam R Karpf; Amarnath Natarajan
Journal:  Chem Biol Drug Des       Date:  2020-04-22       Impact factor: 2.817

4.  NF-κB Blockade with Oral Administration of Dimethylaminoparthenolide (DMAPT), Delays Prostate Cancer Resistance to Androgen Receptor (AR) Inhibition and Inhibits AR Variants.

Authors:  Katherine L Morel; Anis A Hamid; John G Clohessy; Nicole Pandell; Leigh Ellis; Christopher J Sweeney
Journal:  Mol Cancer Res       Date:  2021-04-16       Impact factor: 5.852

5.  Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II.

Authors:  Courtney L Jones; Brett M Stevens; Angelo D'Alessandro; Rachel Culp-Hill; Julie A Reisz; Shanshan Pei; Annika Gustafson; Nabilah Khan; James DeGregori; Daniel A Pollyea; Craig T Jordan
Journal:  Blood       Date:  2019-05-17       Impact factor: 25.476
  5 in total

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