| Literature DB >> 27886912 |
Di Sun1, Peck Y Ong2.
Abstract
Atopic dermatitis is characterized by the interplay of skin barrier defects with the immune system and skin microbiome that causes patients to be at risk for infectious complications. This article reviews the pathogenesis of atopic dermatitis and the mechanisms through which patients are at risk for infection from bacterial, viral, and fungal pathogens. Although these complications may be managed acutely, prevention of secondary infections depends on a multipronged approach in the maintenance of skin integrity, control of flares, and microbial pathogens. Copyright ÂEntities:
Keywords: Atopic dermatitis; Eczema herpeticum; Innate; Keratinocytes; Staphylococcal aureus
Mesh:
Year: 2017 PMID: 27886912 DOI: 10.1016/j.iac.2016.08.015
Source DB: PubMed Journal: Immunol Allergy Clin North Am ISSN: 0889-8561 Impact factor: 3.479