Literature DB >> 27884306

Commentary for "human kidney pericytes produce renin".

Armin Kurtz1.   

Abstract

Renin-secreting cells of the kidney display several particularities, including their intrarenal localization in the fetal and in the adult kidney, their ultrastructure, and the mode by which they secrete renin into circulation to trigger the activity of the renin-angiotensin-aldosterone system. The cell type from which renin cells differentiate has long been subject to speculation. The paper by Stefanska et al. now strongly suggests that renin cells are or derive from pericytes.
Copyright © 2016 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.

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Year:  2016        PMID: 27884306     DOI: 10.1016/j.kint.2016.08.018

Source DB:  PubMed          Journal:  Kidney Int        ISSN: 0085-2538            Impact factor:   10.612


  1 in total

1.  Treatment combining aliskiren with paricalcitol is effective against progressive renal tubulointerstitial fibrosis via dual blockade of intrarenal renin.

Authors:  Sungjin Chung; Soojeong Kim; Minyoung Kim; Eun Sil Koh; Seok Joon Shin; Cheol Whee Park; Yoon Sik Chang; Ho-Shik Kim
Journal:  PLoS One       Date:  2017-07-28       Impact factor: 3.240

  1 in total

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