Literature DB >> 27883897

hnRNPA2/B1 Function in Neurodegeneration: It's a Gain, Not a Loss.

Saskia Hutten1, Dorothee Dormann2.   

Abstract

hnRNPA2B1 is linked to several neurodegenerative disorders, yet its roles in the CNS have been largely unknown. In this issue of Neuron, Martinez et al. (2016) present the first transcriptome-wide analysis of hnRNPA2B1 targets and function in the nervous system.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2016        PMID： 27883897     DOI： 10.1016/j.neuron.2016.11.014

Source DB:  PubMed          Journal:  Neuron        ISSN： 0896-6273            Impact factor:   17.173


  5 in total

Review 1.  Examining the relationship between astrocyte dysfunction and neurodegeneration in ALS using hiPSCs.

Authors:  Madeline Halpern; Kristen J Brennand; James Gregory
Journal:  Neurobiol Dis       Date:  2019-08-02       Impact factor: 5.996

2.  A New Rat Model of Chronic Cerebral Hypoperfusion Resulting in Early-Stage Vascular Cognitive Impairment.

Authors:  Jinxin Wang; Chenyi Yang; Haiyun Wang; Dongxue Li; Tang Li; Yi Sun; Mingshu Zhao; Ji Ma; Wei Hua; Zhuo Yang
Journal:  Front Aging Neurosci       Date:  2020-04-15       Impact factor: 5.750

3.  The methyltransferase SETD2 couples transcription and splicing by engaging mRNA processing factors through its SHI domain.

Authors:  Saikat Bhattacharya; Michaella J Levy; Ning Zhang; Hua Li; Laurence Florens; Michael P Washburn; Jerry L Workman
Journal:  Nat Commun       Date:  2021-03-04       Impact factor: 14.919

4.  Structural basis of the interaction between SETD2 methyltransferase and hnRNP L paralogs for governing co-transcriptional splicing.

Authors:  Saikat Bhattacharya; Suman Wang; Divya Reddy; Siyuan Shen; Ying Zhang; Ning Zhang; Hua Li; Michael P Washburn; Laurence Florens; Yunyu Shi; Jerry L Workman; Fudong Li
Journal:  Nat Commun       Date:  2021-11-08       Impact factor: 14.919

5.  Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1.

Authors:  Baixing Wu; Shichen Su; Deepak P Patil; Hehua Liu; Jianhua Gan; Samie R Jaffrey; Jinbiao Ma
Journal:  Nat Commun       Date:  2018-01-29       Impact factor: 14.919
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.