Literature DB >> 27878777

Vitamin K supplementation to prevent hemorrhagic morbidity and mortality of newborns in India and China.

Rajesh Kumar Rai1, Jing Luo2, Theodore Herzl Tulchinsky2.   

Abstract

BACKGROUND: Vitamin K deficiency bleeding (VKDB) can cause prolonged and bleeding (intracranial hemorrhage) among newborns, which can be life-threatening or lead to long-term morbidity. The aim of this review article is to reiterate empirical evidence to support the argument that vitamin K should be mandatory for newborns in India and China, as well as in other countries with a high burden of neonatal deaths. DATA SOURCES: Studies were integrated from the PubMed/MEDLINE database search, as well as related literature available elsewhere.
RESULTS: Both India and China have been slow in adopting an effective program for administering vitamin K injections to newborns to prevent VKDB-related morbidity and mortality. VKDB cases in China and India have shown inadequate attention to routine use of vitamin K by injection.
CONCLUSIONS: While no reliable data are publicly available, the issue of VKDB is at last receiving some attention from the Chinese public health system as well as the Indian government. In both countries, routine vitamin K administration to newborns would prove to be a cost-effective intervention to reduce preventable neonatal morbidity and mortality. VKDB is a global neonatal care issue, including countries where parental resistance is preventing babies from defense against this life-threatening condition.

Entities:  

Keywords:  global health; hemorrhagic disease of the newborn; intracranial hemorrhage; neonatal mortality; vitamin K deficiency bleeding disorder

Mesh:

Substances:

Year:  2016        PMID: 27878777     DOI: 10.1007/s12519-016-0062-6

Source DB:  PubMed          Journal:  World J Pediatr            Impact factor:   2.764


  23 in total

1.  Neonatal vitamin K prophylaxis in Great Britain and Ireland: the impact of perceived risk and product licensing on effectiveness.

Authors:  Alison Busfield; Andrew McNinch; John Tripp
Journal:  Arch Dis Child       Date:  2007-05-30       Impact factor: 3.791

Review 2.  Vitamin K deficiency bleeding (VKDB) in early infancy.

Authors:  Martin J Shearer
Journal:  Blood Rev       Date:  2008-09-19       Impact factor: 8.250

3.  Intracranial haemorrhage due to late onset vitamin K deficiency bleeding in Hanoi province, Vietnam.

Authors:  N Danielsson; D P Hoa; N V Thang; T Vos; P M Loughnan
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2004-11       Impact factor: 5.747

Review 4.  Vitamin K nutrition, metabolism, and requirements: current concepts and future research.

Authors:  Martin J Shearer; Xueyan Fu; Sarah L Booth
Journal:  Adv Nutr       Date:  2012-03-01       Impact factor: 8.701

Review 5.  Prophylactic vitamin K for vitamin K deficiency bleeding in neonates.

Authors:  R M Puckett; M Offringa
Journal:  Cochrane Database Syst Rev       Date:  2000

6.  Intracranial hemorrhage in late hemorrhagic disease of the newborn.

Authors:  Puneet A Pooni; Daljit Singh; Harmesh Singh; B K Jain
Journal:  Indian Pediatr       Date:  2003-03       Impact factor: 1.411

7.  Factors associated with childhood cancer in a national cohort study.

Authors:  J Golding; M Paterson; L J Kinlen
Journal:  Br J Cancer       Date:  1990-08       Impact factor: 7.640

8.  Vitamin K and childhood cancer: analysis of individual patient data from six case-control studies.

Authors:  E Roman; N T Fear; P Ansell; D Bull; G Draper; P McKinney; J Michaelis; S J Passmore; R von Kries
Journal:  Br J Cancer       Date:  2002-01-07       Impact factor: 7.640

9.  Global, regional, and national causes of child mortality in 2000-13, with projections to inform post-2015 priorities: an updated systematic analysis.

Authors:  Li Liu; Shefali Oza; Daniel Hogan; Jamie Perin; Igor Rudan; Joy E Lawn; Simon Cousens; Colin Mathers; Robert E Black
Journal:  Lancet       Date:  2014-09-30       Impact factor: 79.321

10.  Vitamin K and childhood cancer: a report from the United Kingdom Childhood Cancer Study.

Authors:  N T Fear; E Roman; P Ansell; J Simpson; N Day; O B Eden
Journal:  Br J Cancer       Date:  2003-10-06       Impact factor: 7.640

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  1 in total

Review 1.  Role of Vitamin K in Intestinal Health.

Authors:  Yujiao Lai; Hori Masatoshi; Yanbo Ma; Yuming Guo; Bingkun Zhang
Journal:  Front Immunol       Date:  2022-01-05       Impact factor: 7.561

  1 in total

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