Literature DB >> 27878155

Spin-labelled diketopiperazines and peptide-peptoid chimera by Ugi-multi-component-reactions.

Haider N Sultani1, Haleh H Haeri, Dariush Hinderberger, Bernhard Westermann.   

Abstract

For the first time, spin-labelled coumpounds have been obtained by isonitrile-based multi component reactions (IMCRs). The typical IMCR Ugi-protocols offer a simple experimental setup allowing structural variety by which labelled diketopiperazines (DKPs) and peptide-peptoid chimera have been synthesized. The reaction keeps the paramagnetic spin label intact and offers a simple and versatile route to a large variety of new and chemically diverse spin labels.

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Year:  2016        PMID: 27878155     DOI: 10.1039/c6ob02194h

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  2 in total

1.  Access to New Cytotoxic Triterpene and Steroidal Acid-TEMPO Conjugates by Ugi Multicomponent-Reactions.

Authors:  Haider N Sultani; Ibrahim Morgan; Hidayat Hussain; Andreas H Roos; Haleh H Haeri; Goran N Kaluđerović; Dariush Hinderberger; Bernhard Westermann
Journal:  Int J Mol Sci       Date:  2021-07-01       Impact factor: 5.923

Review 2.  Two decades of recent advances of Ugi reactions: synthetic and pharmaceutical applications.

Authors:  Manar Ahmed Fouad; Hamida Abdel-Hamid; Mohammed Salah Ayoup
Journal:  RSC Adv       Date:  2020-11-23       Impact factor: 4.036

  2 in total

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