Literature DB >> 27876626

Life-threatening NLRC4-associated hyperinflammation successfully treated with IL-18 inhibition.

Scott W Canna1, Charlotte Girard2, Louise Malle3, Adriana de Jesus3, Neil Romberg4, Judith Kelsen4, Lea F Surrey4, Pierre Russo4, Andrew Sleight5, Eduardo Schiffrin5, Cem Gabay2, Raphaela Goldbach-Mansky3, Edward M Behrens4.   

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Year:  2016        PMID： 27876626      PMCID： PMC5846100          DOI： 10.1016/j.jaci.2016.10.022

Source DB:  PubMed          Journal:  J Allergy Clin Immunol        ISSN： 0091-6749            Impact factor:   10.793


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  9 in total

1.  Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis.

Authors:  Roni Nowarski; Ruaidhrí Jackson; Nicola Gagliani; Marcel R de Zoete; Noah W Palm; Will Bailis; Jun Siong Low; Christian C D Harman; Morven Graham; Eran Elinav; Richard A Flavell
Journal:  Cell       Date:  2015-12-03       Impact factor: 41.582

Review 2.  Molecular mechanisms in genetically defined autoinflammatory diseases: disorders of amplified danger signaling.

Authors:  Adriana Almeida de Jesus; Scott W Canna; Yin Liu; Raphaela Goldbach-Mansky
Journal:  Annu Rev Immunol       Date:  2015-02-20       Impact factor: 28.527

3.  Increased serum levels of interferon-gamma-inducible protein 10 and monokine induced by gamma interferon in patients with haemophagocytic lymphohistiocytosis.

Authors:  H Takada; Y Takahata; A Nomura; S Ohga; Y Mizuno; T Hara
Journal:  Clin Exp Immunol       Date:  2003-09       Impact factor: 4.330

4.  Defective phosphorylation of interleukin-18 receptor beta causes impaired natural killer cell function in systemic-onset juvenile idiopathic arthritis.

Authors:  Wilco de Jager; Sebastiaan J Vastert; Jeffrey M Beekman; Nico M Wulffraat; Wietse Kuis; Paul J Coffer; Berent J Prakken
Journal:  Arthritis Rheum       Date:  2009-09

5.  Elevated serum levels of free interleukin-18 in adult-onset Still's disease.

Authors:  Charlotte Girard; Jürgen Rech; Michael Brown; Danièle Allali; Pascale Roux-Lombard; François Spertini; Eduardo J Schiffrin; Georg Schett; Bernhard Manger; Sylvette Bas; Greg Del Val; Cem Gabay
Journal:  Rheumatology (Oxford)       Date:  2016-09-10       Impact factor: 7.580

6.  An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder.

Authors:  Michael B Jordan; David Hildeman; John Kappler; Philippa Marrack
Journal:  Blood       Date:  2004-04-06       Impact factor: 22.113

7.  A multicentre, randomised, double-blind, placebo-controlled trial with the interleukin-1 receptor antagonist anakinra in patients with systemic-onset juvenile idiopathic arthritis (ANAJIS trial).

Authors:  Pierre Quartier; Florence Allantaz; Rolando Cimaz; Pascal Pillet; Claude Messiaen; Christophe Bardin; Xavier Bossuyt; Anne Boutten; Jacques Bienvenu; Agnes Duquesne; Olivier Richer; Damien Chaussabel; Agnes Mogenet; Jacques Banchereau; Jean-Marc Treluyer; Paul Landais; Virginia Pascual
Journal:  Ann Rheum Dis       Date:  2010-12-20       Impact factor: 19.103

8.  An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome.

Authors:  Scott W Canna; Adriana A de Jesus; Sushanth Gouni; Stephen R Brooks; Bernadette Marrero; Yin Liu; Michael A DiMattia; Kristien J M Zaal; Gina A Montealegre Sanchez; Hanna Kim; Dawn Chapelle; Nicole Plass; Yan Huang; Alejandro V Villarino; Angelique Biancotto; Thomas A Fleisher; Joseph A Duncan; John J O'Shea; Susanne Benseler; Alexei Grom; Zuoming Deng; Ronald M Laxer; Raphaela Goldbach-Mansky
Journal:  Nat Genet       Date:  2014-09-14       Impact factor: 38.330

9.  Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation.

Authors:  Neil Romberg; Khatoun Al Moussawi; Carol Nelson-Williams; Amy L Stiegler; Erin Loring; Murim Choi; John Overton; Eric Meffre; Mustafa K Khokha; Anita J Huttner; Brian West; Nikolai A Podoltsev; Titus J Boggon; Barbara I Kazmierczak; Richard P Lifton
Journal:  Nat Genet       Date:  2014-09-14       Impact factor: 38.330
  9 in total
  102 in total

1.  Indeed, IL-18 is more than an inducer of IFN-γ.

Authors:  Charles Anthony Dinarello; Gilles Kaplanski
Journal:  J Leukoc Biol       Date:  2018-05-07       Impact factor: 4.962

Review 2.  Inflammasomes and intestinal inflammation.

Authors:  N Zmora; M Levy; M Pevsner-Fishcer; E Elinav
Journal:  Mucosal Immunol       Date:  2017-04-12       Impact factor: 7.313

Review 3.  Genomics, Biology, and Human Illness: Advances in the Monogenic Autoinflammatory Diseases.

Authors:  Hirotsugu Oda; Daniel L Kastner
Journal:  Rheum Dis Clin North Am       Date:  2017-08       Impact factor: 2.670

4.  Broad detection of bacterial type III secretion system and flagellin proteins by the human NAIP/NLRC4 inflammasome.

Authors:  Valeria M Reyes Ruiz; Jasmine Ramirez; Nawar Naseer; Nicole M Palacio; Ingharan J Siddarthan; Brian M Yan; Mark A Boyer; Daniel A Pensinger; John-Demian Sauer; Sunny Shin
Journal:  Proc Natl Acad Sci U S A       Date:  2017-11-27       Impact factor: 11.205

Review 5.  NLRC4 inflammasomopathies.

Authors:  Neil Romberg; Tiphanie P Vogel; Scott W Canna
Journal:  Curr Opin Allergy Clin Immunol       Date:  2017-12

Review 6.  Molecular mechanisms of phenotypic variability in monogenic autoinflammatory diseases.

Authors:  Ivona Aksentijevich; Oskar Schnappauf
Journal:  Nat Rev Rheumatol       Date:  2021-05-25       Impact factor: 20.543

Review 7.  An Update on Autoinflammatory Diseases: Inflammasomopathies.

Authors:  Cassandra R Harapas; Annemarie Steiner; Sophia Davidson; Seth L Masters
Journal:  Curr Rheumatol Rep       Date:  2018-05-30       Impact factor: 4.592

Review 8.  The monogenic autoinflammatory diseases define new pathways in human innate immunity and inflammation.

Authors:  Kalpana Manthiram; Qing Zhou; Ivona Aksentijevich; Daniel L Kastner
Journal:  Nat Immunol       Date:  2017-07-19       Impact factor: 25.606

Review 9.  The genetics of macrophage activation syndrome.

Authors:  Grant S Schulert; Randy Q Cron
Journal:  Genes Immun       Date:  2020-04-15       Impact factor: 2.676

10.  Systemic Juvenile Idiopathic Arthritis-Associated Lung Disease: Characterization and Risk Factors.

Authors:  Grant S Schulert; Shima Yasin; Brenna Carey; Claudia Chalk; Thuy Do; Andrew H Schapiro; Ammar Husami; Allen Watts; Hermine I Brunner; Jennifer Huggins; Elizabeth D Mellins; Esi M Morgan; Tracy Ting; Bruce C Trapnell; Kathryn A Wikenheiser-Brokamp; Christopher Towe; Alexei A Grom
Journal:  Arthritis Rheumatol       Date:  2019-10-01       Impact factor: 10.995
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