Literature DB >> 2787618

Inhibition of infectivity of human immunodeficiency virus by a novel nucleoside, oxetanocin, and related compounds.

J Seki1, N Shimada, K Takahashi, T Takita, T Takeuchi, H Hoshino.   

Abstract

Oxetanocin is a novel nucleoside containing a 4-membered sugar, oxetanosyl-N-glycoside, and adenine. The effects of oxetanocin and related compounds on the infectivity of human immunodeficiency virus (HIV) were examined. They inhibited HIV infectivity in vitro. Allopurinol and mycophenolic acid produced additive anti-HIV effects when added with these compounds.

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Year:  1989        PMID： 2787618      PMCID： PMC172532          DOI： 10.1128/AAC.33.5.773

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  15 in total

1.  Dextran sulphate, a potent anti-HIV agent in vitro having synergism with zidovudine.

Authors:  R Ueno; S Kuno
Journal:  Lancet       Date:  1987-06-13       Impact factor: 79.321

Review 2.  Strategies for antiviral therapy in AIDS.

Authors:  H Mitsuya; S Broder
Journal:  Nature       Date:  1987 Feb 26-Mar 4       Impact factor: 49.962

Review 3.  Chemotherapeutic approaches to the treatment of the acquired immune deficiency syndrome (AIDS).

Authors:  E De Clercq
Journal:  J Med Chem       Date:  1986-09       Impact factor: 7.446

4.  Infection of HTLV-III/LAV in HTLV-I-carrying cells MT-2 and MT-4 and application in a plaque assay.

Authors:  S Harada; Y Koyanagi; N Yamamoto
Journal:  Science       Date:  1985-08-09       Impact factor: 47.728

5.  Oxetanocin, a novel nucleoside from bacteria.

Authors:  N Shimada; S Hasegawa; T Harada; T Tomisawa; A Fujii; T Takita
Journal:  J Antibiot (Tokyo)       Date:  1986-11       Impact factor: 2.649

6.  Isolation of human immunodeficiency virus from a Japanese hemophilia B patient with AIDS.

Authors:  Y Takeuchi; M Inagaki; N Kobayashi; H Hoshino
Journal:  Jpn J Cancer Res       Date:  1987-01

7.  Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides.

Authors:  H Mitsuya; S Broder
Journal:  Proc Natl Acad Sci U S A       Date:  1986-03       Impact factor: 11.205

8.  Selective inhibition of human cytomegalovirus replication by a novel nucleoside, oxetanocin G.

Authors:  Y Nishiyama; N Yamamoto; K Takahash; N Shimada
Journal:  Antimicrob Agents Chemother       Date:  1988-07       Impact factor: 5.191

9.  Mismatched double-stranded RNA (ampligen) reduces concentration of zidovudine (azidothymidine) required for in-vitro inhibition of human immunodeficiency virus.

Authors:  W M Mitchell; D C Montefiori; W E Robinson; D R Strayer; W A Carter
Journal:  Lancet       Date:  1987-04-18       Impact factor: 79.321

10.  The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial.

Authors:  D D Richman; M A Fischl; M H Grieco; M S Gottlieb; P A Volberding; O L Laskin; J M Leedom; J E Groopman; D Mildvan; M S Hirsch
Journal:  N Engl J Med       Date:  1987-07-23       Impact factor: 91.245
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  5 in total

Review 1.  Mycophenolate mofetil: effects on cellular immune subsets, infectious complications, and antimicrobial activity.

Authors:  M L Ritter; L Pirofski
Journal:  Transpl Infect Dis       Date:  2009-05-26       Impact factor: 2.228

2.  Anti-human immunodeficiency virus activities of nucleosides and nucleotides: correlation with molecular electrostatic potential data.

Authors:  T Mickle; V Nair
Journal:  Antimicrob Agents Chemother       Date:  2000-11       Impact factor: 5.191

Review 3.  Metabolism and mechanism of antiretroviral action of purine and pyrimidine derivatives.

Authors:  J Balzarini
Journal:  Pharm World Sci       Date:  1994-04-15

4.  Effect of oxetanocin G, a novel nucleoside analog, on DNA synthesis by hepatitis B virus virions.

Authors:  T Nagahata; M Kitagawa; K Matsubara
Journal:  Antimicrob Agents Chemother       Date:  1994-04       Impact factor: 5.191

Review 5.  C-C bond forming radical SAM enzymes involved in the construction of carbon skeletons of cofactors and natural products.

Authors:  Kenichi Yokoyama; Edward A Lilla
Journal:  Nat Prod Rep       Date:  2018-07-18       Impact factor: 13.423
  5 in total

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