Tao Wang 1 , Shifu Xiao 2 , Kewei Chen 3 , Cece Yang 1 , Shuhui Dong 1 , Yan Cheng 1 , Xia Li 1 , Jinghua Wang 1 , Minjie Zhu 1 , Fuzhong Yang 1 , Guanjun Li 1 , Ning Su 1 , Yuanyuan Liu 1 , Jing Dai 1 , Mingyuan Zhang 1 Show Affiliations »
Abstract
BACKGROUND: Amnestic MCI (aMCI) has notably increased in Shanghai, China. OBJECTIVE: The study was designed to estimate the prevalence and incidence rates of aMCI and to determine the risk and protective factors for aMCI among persons ≥ 60 years-old and ≥ 70 years-old in Shanghai communities, respectively. METHOD: We carried out this 1-year longitudinal study to survey a random sample of 1,302 individuals ≥ 60 years-old, to collect baseline and follow-up data about lifestyle through self-reports, and vascular and comorbid conditions from medical records and a physical examination. We also analyzed a subgroup of individuals ≥ 70 years-old. RESULTS: The prevalence rate of aMCI in persons ≥ 60 years-old was 22.3%, and the incidence rate (per 1,000 person-years) was 96.9. Being female was a risk factor for aMCI; protective factors included smoking, drinking tea, engaging in intellectual work before retirement, social activities and hobbies, regular reading habits, and surfing the internet. The prevalence rate of aMCI in persons ≥ 70 years was 30.3%, and the incidence rate was 145.6. Smoking, drinking tea, and surfing the internet were not protective factors for this age group (≥ 70 years). CONCLUSION: The present study indicates that aMCI is a considerable health problem in Shanghai. Preventive strategies for aMCI are needed to enhance lifestyle factors that promote brain activity. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.
BACKGROUND: Amnestic MCI (aMCI) has notably increased in Shanghai, China. OBJECTIVE: The study was designed to estimate the prevalence and incidence rates of aMCI and to determine the risk and protective factors for aMCI among persons ≥ 60 years-old and ≥ 70 years-old in Shanghai communities, respectively. METHOD: We carried out this 1-year longitudinal study to survey a random sample of 1,302 individuals ≥ 60 years-old, to collect baseline and follow-up data about lifestyle through self-reports, and vascular and comorbid conditions from medical records and a physical examination. We also analyzed a subgroup of individuals ≥ 70 years-old. RESULTS: The prevalence rate of aMCI in persons ≥ 60 years-old was 22.3%, and the incidence rate (per 1,000 person -years) was 96.9. Being female was a risk factor for aMCI; protective factors included smoking, drinking tea, engaging in intellectual work before retirement, social activities and hobbies, regular reading habits, and surfing the internet. The prevalence rate of aMCI in persons ≥ 70 years was 30.3%, and the incidence rate was 145.6. Smoking, drinking tea, and surfing the internet were not protective factors for this age group (≥ 70 years). CONCLUSION: The present study indicates that aMCI is a considerable health problem in Shanghai. Preventive strategies for aMCI are needed to enhance lifestyle factors that promote brain activity. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.
Entities: Disease
Species
Keywords:
Amnestic mild cognitive impairment; incidence; odds ratio; prevalence; protective factor; risk factor.
Mesh： See more »
Year: 2017
PMID： 27875948 DOI： 10.2174/1567205013666161122094208
Source DB: PubMed Journal: Curr Alzheimer Res ISSN： 1567-2050 Impact factor: 3.498