| Literature DB >> 27875681 |
Domenico F Galati1, Brian J Mitchell2, Chad G Pearson3.
Abstract
Centrioles acquire subdistal appendages (sDAPs) during primary cilium formation. In this issue of Developmental Cell, Mazo et al. (2016) demonstrate that sDAPs keep cilia submerged within deep membrane invaginations. When sDAPs and centrosome cohesion are disrupted, cilia surface to the plasma membrane, which may alter mechanical and chemical signal transduction.Entities:
Mesh:
Year: 2016 PMID: 27875681 DOI: 10.1016/j.devcel.2016.11.006
Source DB: PubMed Journal: Dev Cell ISSN: 1534-5807 Impact factor: 12.270