Literature DB >> 27874898

Polymer-mediated ternary supramolecular interactions for sensitive detection of peptides.

Mahalia A C Serrano1, Huan He1, Bo Zhao1, Rajasekhar R Ramireddy1, Richard W Vachet1, S Thayumanavan1.   

Abstract

A combination of donor-acceptor and electrostatic interactions in a three-component supramolecular system has been shown to form the basis for selective and sensitive detection of peptides. Different substituents in the polymer and the detection matrix were compared to demonstrate that the favorable donor-acceptor interactions explain the observed signal enhancement. The ternary supramolecular interactions discovered in this work are enabled by the self-packing behavior of amphiphilic homopolymers and their ability to mediate interactions between the detection matrix and peptide that facilitate sensitive detection of peptides.

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Year:  2016        PMID： 27874898      PMCID： PMC5167624          DOI： 10.1039/c6an01591c

Source DB:  PubMed          Journal:  Analyst        ISSN： 0003-2654            Impact factor:   4.616


  26 in total

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3.  Sequential Nucleophilic "Click" Reactions for Functional Amphiphilic Homopolymers.

Authors:  Huan He; Bin Liu; Meizhe Wang; Richard W Vachet; S Thayumanavan
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4.  Improved mass spectrometric detection of acidic peptides by variations in the functional group pKa values of reverse micelle extraction agents.

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5.  Self-assembly of random co-polymers for selective binding and detection of peptides.

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6.  Altering the Peptide Binding Selectivity of Polymeric Reverse Micelle Assemblies via Metal Ion Loading.

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  6 in total

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