Literature DB >> 27873455

Catalytic Asymmetric Reductive Condensation of N-H Imines: Synthesis of C2 -Symmetric Secondary Amines.

Vijay N Wakchaure1, Benjamin List1.   

Abstract

A highly diastereoselective and enantioselective Brønsted acid catalyzed reductive condensation of N-H imines was developed. This reaction is catalyzed by a chiral disulfonimide (DSI), uses Hantzsch esters as a hydrogen source, and delivers useful C2 -symmetric secondary amines.
© 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  Brønsted acids; C2-symmetric secondary amines; disulfonimide; organocatalysis; reduction

Year:  2016        PMID： 27873455     DOI： 10.1002/anie.201608329

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  3 in total

1.  Unified Synthesis of Polycyclic Alkaloids by Complementary Carbonyl Activation*.

Authors:  Guoli He; Benjamin List; Mathias Christmann
Journal:  Angew Chem Int Ed Engl       Date:  2021-05-01       Impact factor: 15.336

Review 2.  Chiral Phosphoric Acids as Versatile Tools for Organocatalytic Asymmetric Transfer Hydrogenations.

Authors:  Ádám Márk Pálvölgyi; Fabian Scharinger; Michael Schnürch; Katharina Bica-Schröder
Journal:  European J Org Chem       Date:  2021-10-14

3.  Ternary complexes of chiral disulfonimides in transfer-hydrogenation of imines: the relevance of late intermediates in ion pair catalysis.

Authors:  Matej Žabka; Ruth M Gschwind
Journal:  Chem Sci       Date:  2021-11-17       Impact factor: 9.825
  3 in total

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